Kamiya T, Yasui T, Yokomori H, Nakamoto H, Maruyama T, Suzuki O, Ookawa H, Kiryu Y, Yasumura K, Kakumoto Y
Dept. of Internal Medicine, Keiyu General Hospital.
Gan No Rinsho. 1988 Jan;34(1):97-106.
We have experienced two male cases of an adrenocortical carcinoma that have produced steroid hormones without endocrinological symptoms. Both men were admitted to hospital because of an abdominal pain and left hypochondral tumors. In each case, an abdominal CT, an ultrasonogram and an angiogram demonstrated a left adrenal tumor, and levels of blood dehydroepiandrosterone sulfate, etiocholanolone, pregnenolone sulfate and urine 17 KS were elevated. The tumors were resected and the histology revealed that they were adrenocortical carcinomas. Postoperatively, the levels of their urine hormones returned to normal values, though in one man recurrence occurred a year later. Only 8 cases of an adrenocortical carcinoma that has produced steroids without specific endocrinological symptoms have been reported in Japan, and we also report on two cases herein.
我们遇到过两例肾上腺皮质癌男性病例，肿瘤分泌甾体激素但无内分泌症状。两名男性均因腹痛和左季肋部肿物入院。每例患者经腹部CT、超声和血管造影检查均显示左侧肾上腺肿瘤，血硫酸脱氢表雄酮、本胆烷醇酮、硫酸孕烯醇酮水平及尿17酮升高。肿瘤切除术后，组织学检查显示为肾上腺皮质癌。术后，两名患者尿激素水平恢复正常，但其中一名男性在一年后复发。在日本，仅有8例肾上腺皮质癌分泌甾体激素但无特异性内分泌症状的病例报告，本文我们也报告两例。
