Kalra Sanjay, Gupta Yashdeep
Department of Endocrinology, Bharti Hospital, Karnal, India.
Department of Endocrinology, All India Institute of Medical Sciences, New Delhi, India.
Eur Endocrinol. 2015 Aug;11(2):79-80. doi: 10.17925/EE.2015.11.02.79. Epub 2015 Aug 19.
This editorial focuses on appropriate terminology related to basal insulin therapy. The authors analyse current usage of 'basal insulin failure', and propose 'basal insulin inadequacy' as a better descriptor for persons not responding to basal insulin alone. The pharmacokinetic and pharmacodynamic differences between various basal insulin preparations are highlighted. Based upon these, a drug-specific definition for insulin inadequacy is suggested, instead of a generic class-based labelling.
本社论聚焦于与基础胰岛素治疗相关的恰当术语。作者分析了“基础胰岛素失效”一词的当前用法，并提出“基础胰岛素不足”作为对仅使用基础胰岛素无反应者的更合适描述。文中强调了各种基础胰岛素制剂之间的药代动力学和药效学差异。基于这些差异，建议针对胰岛素不足给出特定药物的定义，而非基于通用类别的标签。
