肉瘤继发的肿瘤性骨软化症
Tumour-induced Osteomalacia Secondary to a Sarcoma.
作者信息
Rodriguez-Velver Karla Victoria, Zapata-Rivera María Azucena, Montes-Villarreal Juan, Lavalle-Gonzâlez Fernando Javier, González-González José Gerardo, Villarreal-Pérez Jesús Zacarías, Rodríguez-Gutierrez Rene
机构信息
Endocrinology Division, University Hospital "Dr. Jose E. Gonzalez", Medical School, Autonomous University of Nuevo Leon, Monterrey, Mexico.
Knowledge and Evaluation Research Unit in Endocrinology, Mayo Clinic, Rochester, Minnesota, US.
出版信息
Eur Endocrinol. 2016 Aug;12(2):104-106. doi: 10.17925/EE.2016.12.02.104. Epub 2016 Aug 28.
Tumour-induced osteomalacia (TIO), is a rare paraneoplasatic syndrome found in >95% of benign tumours that secrete fibroblast growth factor 23 - a phosphaturic circulating hormone. A rare case of a TIO secondary to a sarcoma, in a 21-year old man with history of bone fractures and distinctive physical and biochemical characteristics is presented and discussed.
肿瘤诱导的骨软化症（TIO）是一种罕见的副肿瘤综合征，在95%以上分泌成纤维细胞生长因子23（一种促尿磷排泄的循环激素）的良性肿瘤中发现。本文报告并讨论了一例继发于肉瘤的TIO罕见病例，患者为一名21岁男性，有骨折病史，具有独特的体格检查和生化特征。
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