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[膀胱水扩张术治疗间质性膀胱炎/膀胱疼痛综合征患者]

[Bladder hydrodistension in treating patients with interstytial cystitis/ bladder pain syndrome].

作者信息

Al'-Shukri S Kh, Kuz'min I V, Slesarevskaya M N, Ignashov Yu A

机构信息

Department of Urology, First Pavlov State Medical University of St. Petersburg, St. Petersburg, Russia.

出版信息

Urologiia. 2018 Mar(1):26-29.

Abstract

UNLABELLED

This study aimed to evaluate the effectiveness of bladder hydrodistension in the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS), depending on the duration of the procedure.

MATERIALS AND METHODS

The study comprised 71 women aged 51.6+/-8.3 years with a 5.2+/-2.3 year history of IC/BPS. All patients underwent bladder hydrodistension (BH). Depending on the duration of BH, patients were divided into 4 groups. The distension time in group 1 (n=10), group 2 (n=20), group 3 (n=20) and group 4 (n=21) was 1 min, 2 min, 4 min and 6 min, respectively. The treatment effectiveness was assessed 1 month after BH by subjective assessment of patients, Pelvic Pain and Urgency/Frequency (PUF) Patient Symptom Scale questionnaire, a visual analog pain scale (VAS), and voiding diaries.

RESULTS

At one month after BH, positive effect was observed in 32 (45.1%) patients. In groups 1, 2, 3 and 4 the treatment was effective in 20%, 55%, 45% and 47.6% of patients, respectively. Clinical effectiveness of BH with distension time of 1 min was significantly lower than that of 2, 4, and 6 min. At the same time, we did not find significant differences in the effectiveness of this procedure with distension time of 2, 4 and 6 min.

CONCLUSION

The results of this study suggest that BH is an effective treatment in patients suffering from IC/BPS. At the same time, they show that the distension time of 2 min. is optimal from the point of view of clinical effectiveness, since the longer duration of the procedure is excessive, and the shorter time is insufficient.

摘要

未标注

本研究旨在根据膀胱水扩张术的持续时间,评估其治疗间质性膀胱炎/膀胱疼痛综合征(IC/BPS)的有效性。

材料与方法

本研究纳入了71名年龄为51.6±8.3岁、患有IC/BPS 5.2±2.3年的女性患者。所有患者均接受了膀胱水扩张术(BH)。根据BH的持续时间,患者被分为4组。第1组(n = 10)、第2组(n = 20)、第3组(n = 20)和第4组(n = 21)的扩张时间分别为1分钟、2分钟、4分钟和6分钟。在BH术后1个月,通过患者主观评估、盆腔疼痛与尿急/尿频(PUF)患者症状量表问卷、视觉模拟疼痛量表(VAS)和排尿日记来评估治疗效果。

结果

BH术后1个月,32名(45.1%)患者观察到积极效果。在第1组、第2组、第3组和第4组中,治疗有效的患者分别为20%、55%、45%和47.6%。扩张时间为1分钟的BH临床疗效显著低于2分钟、4分钟和6分钟的。同时,我们未发现扩张时间为2分钟、4分钟和6分钟的该手术在疗效上有显著差异。

结论

本研究结果表明,BH是治疗IC/BPS患者的有效方法。同时,研究结果表明,从临床疗效角度来看,2分钟的扩张时间是最佳的,因为手术时间过长则多余,过短则不足。

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