巨细胞病毒装配完全是管状的。
HCMV Assembly Is Totally Tubular.
机构信息
Institute for Molecular Virology and McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI 53706, USA.
出版信息
Dev Cell. 2018 Apr 9;45(1):1-2. doi: 10.1016/j.devcel.2018.03.014.
PMID:29634930
Abstract
Microtubules are normally organized at centrosomes, but other sites can also serve as microtubule organizing centers (MTOCs). In this issue of Developmental Cell, Procter et al. (2018) show that the human cytomegalovirus virion assembly compartment acts as a dynamic Golgi-derived MTOC where EB3 nucleates microtubules and regulates infectious virion production.
摘要
微管通常在中心体处组织，但其他部位也可以作为微管组织中心（MTOC）。在本期《发育细胞》中，Procter 等人（2018）表明，人巨细胞病毒病毒粒子组装隔室充当动态的高尔基体衍生的 MTOC，EB3 在该处起始微管并调节感染性病毒粒子的产生。
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