University of Ottawa, Ottawa, Ontario, Canada.
University of Ottawa, Ottawa, Ontario, Canada; Institut du Savoir, l'Hopital Montfort, Ottawa, Ontario, Canada; University of Ottawa Brain and Mind Research Institute, Ottawa, Ontario, Canada.
Psychiatry Res. 2018 Jun;264:155-161. doi: 10.1016/j.psychres.2018.04.003. Epub 2018 Apr 3.
Little is known about the beliefs people with panic disorder (PD) have about their illness and how these beliefs might influence treatment outcome. This study explored demographic and clinical predictors of etiological beliefs about PD and the impact these beliefs have on treatment response. The sample included 251 outpatients with PD who participated in a randomized placebo-controlled trial of treatments for PD. Regression analyses revealed that sex, duration of PD and family history of psychiatric illnesses predicted biological etiological beliefs, previous history of psychotherapy predicted environmental etiological beliefs, and age, impaired functioning, and measures of "fear of fear" predicted multiple etiological beliefs about PD. Etiological beliefs predicted more severe symptoms at 12 weeks post-treatment, irrespective of the type of treatment received, but had no effect on attrition, treatment adherence or treatment-related adverse effects This study contributes to the sparse literature on etiological beliefs about PD. Results are preliminary and further research is needed to understand more fully the factors that shape etiological beliefs about PD, whether these beliefs change over the course of illness, and the impact etiological beliefs have on treatment outcome.
关于惊恐障碍（PD）患者对自身疾病的信念知之甚少，这些信念如何影响治疗结果也不清楚。本研究旨在探讨 PD 病因信念的人口统计学和临床预测因素，以及这些信念对治疗反应的影响。该样本包括 251 名参加 PD 治疗的随机安慰剂对照试验的门诊患者。回归分析显示，性别、PD 持续时间和精神疾病家族史预测生物病因信念，以前的心理治疗史预测环境病因信念，年龄、功能受损和“恐惧恐惧”测量预测 PD 的多种病因信念。病因信念预测治疗后 12 周时症状更严重，与所接受的治疗类型无关，但对脱落、治疗依从性或与治疗相关的不良反应没有影响。本研究为 PD 病因信念的稀少文献做出了贡献。结果尚属初步，需要进一步研究以更全面地了解影响 PD 病因信念的因素，这些信念是否会随疾病的发展而变化，以及病因信念对治疗结果的影响。
