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自体造血干细胞移植(SCT)后复发的所有霍奇金淋巴瘤患者是否都应考虑异体 SCT?

Should all patients with Hodgkin lymphoma who relapse after autologous SCT be considered for allogeneic SCT?

机构信息

University College London Cancer Institute, London, United Kingdom.

出版信息

Blood Adv. 2018 Apr 10;2(7):817-820. doi: 10.1182/bloodadvances.2017011122.

DOI:10.1182/bloodadvances.2017011122
PMID:29636327
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5894255/
Abstract

This article has a companion Counterpoint by Moskowitz.

摘要

本文有一篇由 Moskowitz 撰写的相关反论文章。

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Should all patients with Hodgkin lymphoma who relapse after autologous SCT be considered for allogeneic SCT?自体造血干细胞移植(SCT)后复发的所有霍奇金淋巴瘤患者是否都应考虑异体 SCT?
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本文引用的文献

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Post-Transplantation Cyclophosphamide-Based Haploidentical Transplantation as Alternative to Matched Sibling or Unrelated Donor Transplantation for Hodgkin Lymphoma: A Registry Study of the Lymphoma Working Party of the European Society for Blood and Marrow Transplantation.移植后环磷酰胺为基础的单倍体相合移植作为霍奇金淋巴瘤同胞或无关供者移植的替代方案:欧洲血液和骨髓移植学会淋巴瘤工作组的注册研究。
J Clin Oncol. 2017 Oct 20;35(30):3425-3432. doi: 10.1200/JCO.2017.72.6869. Epub 2017 Aug 28.
2
Hodgkin Lymphoma Version 1.2017, NCCN Clinical Practice Guidelines in Oncology.霍奇金淋巴瘤 1.2017 年版,NCCN 肿瘤学临床实践指南。
J Natl Compr Canc Netw. 2017 May;15(5):608-638. doi: 10.6004/jnccn.2017.0064.
3
Phase II Study of the Efficacy and Safety of Pembrolizumab for Relapsed/Refractory Classic Hodgkin Lymphoma.帕博利珠单抗治疗复发/难治性经典型霍奇金淋巴瘤的疗效和安全性II期研究。
J Clin Oncol. 2017 Jul 1;35(19):2125-2132. doi: 10.1200/JCO.2016.72.1316. Epub 2017 Apr 25.
4
Efficacy and tolerability of nivolumab after allogeneic transplantation for relapsed Hodgkin lymphoma.异基因造血干细胞移植后纳武利尤单抗治疗复发霍奇金淋巴瘤的疗效和耐受性。
Blood. 2017 May 4;129(18):2471-2478. doi: 10.1182/blood-2016-11-749556. Epub 2017 Mar 7.
5
Safety and efficacy of allogeneic hematopoietic stem cell transplant after PD-1 blockade in relapsed/refractory lymphoma.复发/难治性淋巴瘤患者接受PD-1阻断治疗后进行异基因造血干细胞移植的安全性和有效性
Blood. 2017 Mar 9;129(10):1380-1388. doi: 10.1182/blood-2016-09-738385. Epub 2017 Jan 10.
6
Nivolumab for classical Hodgkin's lymphoma after failure of both autologous stem-cell transplantation and brentuximab vedotin: a multicentre, multicohort, single-arm phase 2 trial.纳武利尤单抗用于自体干细胞移植和维布妥昔单抗均治疗失败后的经典型霍奇金淋巴瘤:一项多中心、多队列、单臂2期试验。
Lancet Oncol. 2016 Sep;17(9):1283-94. doi: 10.1016/S1470-2045(16)30167-X. Epub 2016 Jul 20.
7
Five-year survival and durability results of brentuximab vedotin in patients with relapsed or refractory Hodgkin lymphoma.复发或难治性霍奇金淋巴瘤患者使用维布妥昔单抗的5年生存率和疗效持久性结果
Blood. 2016 Sep 22;128(12):1562-6. doi: 10.1182/blood-2016-02-699850. Epub 2016 Jul 18.
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Programmed Death-1 Blockade With Pembrolizumab in Patients With Classical Hodgkin Lymphoma After Brentuximab Vedotin Failure.在接受维布妥昔单抗治疗失败的经典型霍奇金淋巴瘤患者中使用帕博利珠单抗进行程序性死亡-1阻断治疗。
J Clin Oncol. 2016 Nov 1;34(31):3733-3739. doi: 10.1200/JCO.2016.67.3467.
9
Impact of Pretransplantation (18)F-Fluorodeoxyglucose-Positron Emission Tomography on Survival Outcomes after T Cell-Depleted Allogeneic Transplantation for Hodgkin Lymphoma.移植前(18)F-氟脱氧葡萄糖-正电子发射断层扫描对霍奇金淋巴瘤T细胞去除异基因移植后生存结果的影响
Biol Blood Marrow Transplant. 2016 Jul;22(7):1234-1241. doi: 10.1016/j.bbmt.2016.03.034. Epub 2016 Apr 14.
10
Role of cytotoxic therapy with hematopoietic cell transplantation in the treatment of Hodgkin lymphoma: guidelines from the American Society for Blood and Marrow Transplantation.细胞毒性疗法联合造血细胞移植在霍奇金淋巴瘤治疗中的作用:美国血液和骨髓移植学会指南
Biol Blood Marrow Transplant. 2015 Jun;21(6):971-83. doi: 10.1016/j.bbmt.2015.02.022. Epub 2015 Mar 12.