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主动脉缩窄手术修复的长期结果——通过运动试验进行评估

Long-term results of surgical repair of coarctation of the aorta--evaluation by exercise test.

作者信息

Katz G, Uretzky G, Beer G, Appelbaum A, Borman J B

机构信息

Department of Cardiothoracic Surgery, Hadassah Hospital, Jerusalem, Israel.

出版信息

Cardiology. 1987;74(6):465-73. doi: 10.1159/000174239.

DOI:10.1159/000174239
PMID:2963693
Abstract

Thirty-six patients have been operated on for coarctation of the aorta. The age at operation ranged from 4 to 45 years with a mean of 14 years. Preoperative systolic blood pressure (BP) was above the normal mean + 2 SD in 34 (94%) of the patients. The surgical techniques used for correction of coarctation were: resection and end-to-end anastomosis (50%), resection and graft interposition (25%), patch graft angioplasty (22%) and subclavian artery to descending aorta bypass graft (3%). There was no hospital mortality. Systolic BP measured on hospital discharge available in 30 patients showed an average decrease of 26 mm Hg. The mean follow-up period in 16 of 30 patients (53%) was 7.2 years. All of these patients had a further decrease in systolic BP, and in 14 of 16 (87%) BP was within the mean + 2 SD. Twelve patients were examined in the vascular diagnostic laboratory to determine adequacy of the repair by hemodynamic measures. After average of 7.8 years following operation, all of them had ankle systolic BP higher than brachial systolic pressure; ankle BP did not drop after treadmill walking exercise and the directional Doppler velocity curves from the legs were normal. This study suggested that BP continued to decrease after hospital discharge. We were unable to demonstrate correlation between age at operation and decrease in BP. The adequacy of surgical repair can be assessed by mild effort stress test combined with ankle/arm ratio measurement and directional Doppler velocity curves.

摘要

36例患者接受了主动脉缩窄手术。手术年龄为4至45岁,平均14岁。34例(94%)患者术前收缩压高于正常均值+2标准差。用于矫正主动脉缩窄的手术技术有:切除端端吻合术(50%)、切除移植物植入术(25%)、补片移植血管成形术(22%)和锁骨下动脉至降主动脉旁路移植术(3%)。无医院死亡病例。30例患者出院时测得的收缩压平均下降了26mmHg。30例患者中的16例(53%)平均随访期为7.2年。所有这些患者的收缩压进一步下降,16例中的14例(87%)血压在均值+2标准差范围内。12例患者在血管诊断实验室接受检查,通过血流动力学测量确定修复的充分性。术后平均7.8年后,所有患者的踝部收缩压均高于肱部收缩压; treadmill步行运动后踝部血压未下降,腿部的定向多普勒速度曲线正常。本研究表明,出院后血压持续下降。我们未能证明手术年龄与血压下降之间的相关性。手术修复的充分性可通过轻度运动应激试验结合踝/臂比值测量和定向多普勒速度曲线来评估。

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