Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut.
Department of Psychology, Yale University, New Haven, Connecticut.
Int J Eat Disord. 2018 Jun;51(6):558-564. doi: 10.1002/eat.22860. Epub 2018 Apr 10.
Individuals seeking weight loss treatment have diverse pretreatment weight trajectories, and once enrolled, individuals' response to weight loss treatments also varies greatly and may be influenced by the presence of binge-eating disorder (BED). Reported average weight losses may obscure these considerable differences. This study examined whether BED status and different weight-related change variables are associated with successful weight loss treatment outcomes in a controlled treatment study.
Participants (N = 89) with overweight/obesity, with and without BED, participated in a 3-month weight loss trial in primary care with 3- and 12-month follow-ups. We tested the prognostic significance of four weight-related change variables (the last supper, early weight loss, pretreatment weight trajectory, weight suppression) on outcomes (weight loss-overall, weight loss-"subsequent," weight loss during second half of treatment).
Early weight loss was positively associated with weight loss-overall at post-treatment, and at 3-month and 12-month follow-up. Early weight loss was positively associated with weight loss-subsequent at post-treatment only. No other weight-related variables were significantly associated with weight loss. Models including BED status and treatment condition were not significant.
Participants with early weight loss were more likely to continue losing weight, regardless of BED status or treatment condition. The results highlight the importance of early dedication to weight loss treatment to increase the likelihood of positive outcomes.
寻求减肥治疗的个体在治疗前存在不同的体重变化轨迹,而一旦入组,个体对减肥治疗的反应也存在很大差异,并且可能受到暴食障碍(BED)的影响。报告的平均体重减轻可能掩盖了这些相当大的差异。本研究在一项对照治疗研究中,检查了 BED 状态和不同的体重相关变化变量是否与减肥治疗结果相关。
超重/肥胖的参与者(N=89),无论是否患有 BED,均参加了一项在初级保健中进行的为期 3 个月的减肥试验,并进行了 3 个月和 12 个月的随访。我们测试了四个与体重相关的变化变量(last supper、早期体重减轻、治疗前体重轨迹、体重抑制)对结局(总体体重减轻、后续体重减轻、治疗后半段体重减轻)的预后意义。
早期体重减轻与治疗后、3 个月和 12 个月随访时的总体体重减轻呈正相关。早期体重减轻与治疗后即刻的后续体重减轻呈正相关。其他体重相关变量与体重减轻无关。包括 BED 状态和治疗条件的模型没有显著意义。
早期体重减轻的参与者更有可能继续减肥,无论 BED 状态或治疗条件如何。结果强调了早期致力于减肥治疗以增加积极结果的可能性的重要性。