Demiryürek Bekir Enes, Emre Ufuk, Korucu Osman, Barut Banu Özen, Tascilar Fatma Nida, Atasoy Hüseyin Tuğrul, Demiryürek Esra, Yaylaci Selçuk, Genc Ahmet Bilal
Sakarya Education and Research Hospital Neurology Department Sakarya, Turkey.
Kecioren Education and Research Hospital Neurology Department Ankara, Turkey.
Ideggyogy Sz. 2016 Sep 30;69(9-10):319-325. doi: 10.18071/isz.69.0319.
Metabolic Syndrome (MetS) and headaches are common public health problems in whole world. The relationship between headaches and the MetS isn't understood clearly. Purpose - The aim of this study is to determine the prevalence and types of headaches, and evaluate the relationship between headache characteristics and clinical and laboratory parameters analyzed in patients diagnosed with MetS.
Of the patients diagnosed with MetS in Endocrinology outpatient clinics between July 2011 and July 2012, 202 patients were included in the study. Hemoglobin, fasting blood glucose (FBG), total cholesterol, triglyceride, HDL and LDL cholesterol, thyroid function tests and HbA1c values of all patients were recorded. Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) were applied to all patients. The headache severity was assessed by Visual Analog Scale (VAS).
The prevalence of headache in patients with MetS was found to be 61.4%. The incidence of headache was higher in female patients (F: 86.4%, M: 13.6%). The distribution of the subtypes of headaches was as follows: Episodic Tension-Type Headaches (ETTH) 24.8%, Episodic Migraine 14.4%, Chronic Tension-Type Headaches (CTTH) 11.3%, Episodic Tension-Type Headaches (ETTH) and Episodic Migraine 7.9%, and other types of headaches (Cervicogenic Headache and Cluster Headache) 3%. No statistically significant relationship was found between headache and non-headache groups in terms of body mass index, waist circumference, and the laboratory parameters (p>0.05). The mean BDI and BAI scores were higher in the headache group (p<0.001 and p<0.001). No significant difference was found between the mean MIDAS scores in the subtypes of headaches (p=0.35). In the headache group, there was a significant relationship only between triglyceride levels and attack frequency, duration and severity.
Prevalence of headache in patients with MetS was 61.4%. The incidence of subtypes of headaches was similar to those in the general population. A relationship was found between triglyceride levels and attack frequency and severity. The result may be important to draw attention to the evaluation of triglyceride levels for reducing the frequency and severity of attacks in patients with headaches.
代谢综合征（MetS）和头痛是全球常见的公共卫生问题。头痛与代谢综合征之间的关系尚未完全明确。目的——本研究旨在确定头痛的患病率和类型，并评估头痛特征与诊断为代谢综合征患者的临床及实验室参数之间的关系。
选取2011年7月至2012年7月在内分泌门诊诊断为代谢综合征的患者，202例患者纳入研究。记录所有患者的血红蛋白、空腹血糖（FBG）、总胆固醇、甘油三酯、高密度脂蛋白和低密度脂蛋白胆固醇、甲状腺功能检查及糖化血红蛋白（HbA1c）值。对所有患者应用贝克抑郁量表（BDI）和贝克焦虑量表（BAI）。采用视觉模拟评分法（VAS）评估头痛严重程度。
代谢综合征患者中头痛的患病率为61.4%。女性患者头痛发生率更高（女性：86.4%，男性：13.6%）。头痛亚型分布如下：发作性紧张型头痛（ETTH）24.8%，发作性偏头痛14.4%，慢性紧张型头痛（CTTH）11.3%，发作性紧张型头痛（ETTH）和发作性偏头痛7.9%，其他类型头痛（颈源性头痛和丛集性头痛）3%。头痛组与非头痛组在体重指数、腰围及实验室参数方面未发现统计学显著差异（p>0.05）。头痛组的平均BDI和BAI评分更高（p<0.001和p<0.001）。头痛亚型的平均偏头痛残疾评定量表（MIDAS）评分之间未发现显著差异（p=0.35）。在头痛组中，仅甘油三酯水平与发作频率、持续时间和严重程度之间存在显著关系。
代谢综合征患者中头痛的患病率为61.4%。头痛亚型的发生率与普通人群相似。发现甘油三酯水平与发作频率及严重程度之间存在关系。该结果对于提醒关注甘油三酯水平评估以降低头痛患者发作频率和严重程度可能具有重要意义。
