Frosch P J
Universitäts-Hautklinik Heidelberg.
Z Hautkr. 1987 Dec 1;62(23):1631-4, 1637-8.
We present the patch test results of 2,623 patients treated at the Department of Dermatology, University of Heidelberg, from July, 1984 to June, 1986. One test at least was positive in 680 patients (25.9%). 257 allergens produced a total of 1,450 positive reactions. (average: 2.1 per patient). 9.7% of the allergens caused 64.4% of the positive reactions. The 5 most frequent allergens were nickel sulfate, balsam of Peru, formaldehyde, neomycin sulfate, and cobalt sulfate. Mixed fragrances and Kathon CG were among the 20 most frequent allergens though only tested during half of the study period. Glyceril monothioglycolate was the leading allergen with hairdressers. Other allergens clinically relevant were rubber gloves, bufexamac, bronopol, and propolis.
我们展示了1984年7月至1986年6月期间在海德堡大学皮肤科接受治疗的2623例患者的斑贴试验结果。680例患者(25.9%)至少有一项试验呈阳性。257种变应原共产生1450次阳性反应(平均每位患者2.1次)。9.7%的变应原引起了64.4%的阳性反应。最常见的5种变应原是硫酸镍、秘鲁香脂、甲醛、硫酸新霉素和硫酸钴。混合香料和卡松CG虽然仅在研究期的一半时间内进行检测,但却是20种最常见的变应原之一。巯基乙酸甘油酯是美发师中最主要的变应原。其他具有临床相关性的变应原还有橡胶手套、丁苯羟酸、溴硝丙二醇和蜂胶。