McDermott E A
Advanced Cardiovascular Systems Inc., Mountain View, CA 94039.
Z Kardiol. 1987;76 Suppl 6:29-32.
The technology of coronary guide wires has advanced rapidly since Simpson and Robert performed the first angioplasty with a movable guidewire system in 1981. The technology involved in engineering guidewires encompasses three areas: (1) selection of materials, (2) design of the configuration, and (3) development of the construction process to fabricate the guidewire. Each of these areas must be considered concurrently; that is, the functional effects of manufacturing a wire must be considered along with material selection and configuration design. Another critical area is functional testing to ensure safe and effective performance of the guidewire in the clinical setting and to confirm its functional limits. Research is directed continually toward advancing existing guidewire technology to improve functional performance and develop more efficient manufacturing processes. Additionally under development are new guidewire devices incorporating microsensors and fiberoptics to provide real-time feedback. Advances in technology require miniaturization of guidewire components and application of new materials and processes to manufacture new designs.
自1981年辛普森和罗伯特使用可移动导丝系统进行首次血管成形术以来，冠状动脉导丝技术发展迅速。制造导丝所涉及的技术包括三个方面：（1）材料选择；（2）结构设计；（3）制造导丝的制造工艺开发。这些方面中的每一个都必须同时考虑；也就是说，在选择材料和设计结构的同时，必须考虑制造导丝的功能效果。另一个关键领域是功能测试，以确保导丝在临床环境中安全有效地发挥作用，并确定其功能极限。研究不断致力于改进现有导丝技术，以提高功能性能并开发更高效的制造工艺。此外，正在开发结合微传感器和光纤以提供实时反馈的新型导丝装置。技术进步要求导丝组件小型化，并应用新材料和新工艺来制造新设计。
