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儿科年龄组红细胞浓缩液处方的评估。

Assessment of the prescription of red blood cell concentrates in the pediatric age group.

作者信息

Faria João Carlos Pina, Victorino Camila Augusta, Souza Fabíola Isabel Suano de, Sarni Roseli Oselka Saccardo

机构信息

Faculdade de Medicina do ABC, Santo André, SP, Brazil.

Hospital São Bernardo, São Bernardo do Campo, SP, Brazil.

出版信息

Rev Assoc Med Bras (1992). 2018 Feb;64(2):181-186. doi: 10.1590/1806-9282.64.02.181.

Abstract

OBJECTIVE

To verify the adequacy of red blood cell (RBC) prescription to pediatric patients in different sectors of a pediatric hospital.

METHOD

A retrospective study was conducted including 837/990 RBC transfusion requisition forms for children and adolescents (0 to 13 years old) filed in between January 2007 and April 2015 by the pediatricians of the emergency room (ER), infirmary ward and intensive care unit (pICU). Transfusion requisition forms belonging to patients with chronic anemia or acute hemorrhage, as well as incompletes requisition forms, were excluded.

RESULTS

Trigger, prescribed volume and subtype of RBC concentrates were adequate in 532 (65.3%), 460 (58.8%) and 805 (96.2%) of the transfusions, respectively. When the clinical picture was considered, prescription adequacy was higher compared to the use of the hemoglobin level alone (70.9% vs. 41%). The pICU had the highest correct trigger percentage (343 [71.6%]; p<0.001) while the ER showed more often adequate prescribed volumes (119 [66.1%]; p=0.020). The most common inadequacy regarding volume was that of prescriptions above the recommendation > 15 mL/kg found in 309 cases (36.9%). Thirty-two (32) RBC subtypes were requested and none were consistent with current recommendations.

CONCLUSION

The results obtained in our study showed that RBC transfusion occurred more appropriately when the clinical picture was taken into account at request. There was a tendency to prescribe higher volumes and RBC subtypes without the justification of current protocols. Hemotherapic teachings at undergraduate level and medical residency must be improved.

摘要

目的

验证一家儿童医院不同科室对儿科患者红细胞(RBC)处方的合理性。

方法

进行一项回顾性研究,纳入2007年1月至2015年4月期间急诊室(ER)、医务室病房和重症监护病房(pICU)的儿科医生提交的837份/990份儿童及青少年(0至13岁)红细胞输血申请表。排除患有慢性贫血或急性出血患者的输血申请表以及不完整的申请表。

结果

在分别532例(65.3%)、460例(58.8%)和805例(96.2%)输血中,红细胞浓缩物的触发因素、规定剂量和亚型是合适的。当考虑临床情况时,处方合理性高于仅使用血红蛋白水平时(70.9%对41%)。pICU的正确触发百分比最高(343例[71.6%];p<0.001),而ER的规定剂量更常合适(119例[66.1%];p=0.020)。关于剂量最常见的不合理情况是309例(36.9%)中处方超过推荐剂量>15 mL/kg。共申请了32种红细胞亚型,无一与当前推荐一致。

结论

我们研究的结果表明,在申请时考虑临床情况时红细胞输血更恰当。存在在无现行方案依据的情况下开具更高剂量和红细胞亚型的趋势。本科阶段和住院医师阶段的血液治疗教学必须改进。

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