0.2%聚己缩胍治疗麻风营养性足部溃疡的初步研究

Polyhexanide 0.2% in treatment of trophic foot ulcers in leprosy - preliminary study.

作者信息

Zanchin Túlio Neutzling, Serafini Cássio Battisti, Brandão Francine Silva, Nery José Augusto da Costa

机构信息

Department of Dermatology, Instituto de Dermatologia Prof. Rubem David Azulay - Santa Casa da Misericórdia do Rio de Janeiro (IDPRDA-SCMRJ) - Rio de Janeiro (RJ), Brazil.

Department of Tropical Dermatology, Hospital Central do Exército (HCE) - Rio de Janeiro (RJ), Brazil.

出版信息

An Bras Dermatol. 2018 Jan-Feb;93(1):145-147. doi: 10.1590/abd1806-4841.20186655.

DOI:10.1590/abd1806-4841.20186655

PMID:29641721

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5871386/

Abstract

Leprosy is a chronic infectious disease caused by Mycobacterium leprae, which affects peripheral nerves, skin and mucous membranes. The impairment of neural function as well as sensory or sensory-motor disabilities in leprosy continue to be a problem that requires careful attention in the management of patients with the aim to avoid or minimize their progression to prevent sequelae. One of the most common characteristics of these ulcers is the tendency to chronicity, with variable therapeutic response. In this article, we shall discuss the therapeutic management of thirteen trophic leprosy ulcers in eight patients using polyhexanide 0.2% products.

摘要

麻风病是由麻风分枝杆菌引起的一种慢性传染病，可影响周围神经、皮肤和黏膜。麻风病患者的神经功能损害以及感觉或感觉运动障碍仍然是一个需要在患者管理中予以密切关注的问题，目的是避免或尽量减少其进展以预防后遗症。这些溃疡最常见的特征之一是具有慢性化倾向，治疗反应不一。在本文中，我们将讨论使用0.2%聚己缩胍产品对8例患者的13处营养性麻风溃疡进行的治疗处理。