Li Hai-Yang, Zhao Yuan-Fei, Dai Lu, Xu Shi-Jun, Zhang Hong-Jia, Jiang Wen-Jian
Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China Centre for Transplant and Renal Research, The Westmead Institute for Medical Research, University of Sydney, Sydney, Australia. Beijing Institute of Heart, Lung and Blood Vessel Diseases Beijing Lab for Cardiovascular Precision Medicine Beijing Aortic Disease Center, Cardiovascular Surgery Center Beijing Engineering Research Center for Vascular Prostheses, Beijing, China.
Medicine (Baltimore). 2018 Apr;97(15):e0383. doi: 10.1097/MD.0000000000010383.
Many adult patients with congenital ventricular septal defect (VSD) also developed ascending aortic dilation, but few report the clinical features and surgical management of these patients. This study was designed to study ascending aortic dilation in adult patients with congenital VSD, and summarized the treatment experience and prognosis.To assess the clinical features and surgical management, we performed a retrospective analysis on preoperative data, intraoperative data, and postoperative data from the adult patients with congenital VSD who developed ascending aortic dilation in our institution from February 2010 to December 2016.From February 2010 to December 2016, we operated on 13 adult patients (12 males, 92.31%) with VSD who developed ascending aortic dilation. Median age was 37 (interquartile range 14) years. All patients suffered from perimembranous VSD and received surgical treatment. Their symptoms were all improved after surgery, no deaths occurred.Surgery is feasible for the ascending aortic dilation in adult patients with congenital VSD. Both proper perioperative treatment and close monitoring are required for the successful surgery.
许多成年先天性室间隔缺损（VSD）患者也会出现升主动脉扩张，但很少有关于这些患者临床特征及外科治疗的报道。本研究旨在探讨成年先天性VSD患者的升主动脉扩张情况，并总结治疗经验及预后。为评估临床特征及外科治疗方法，我们对2010年2月至2016年12月在我院发生升主动脉扩张的成年先天性VSD患者的术前、术中和术后数据进行了回顾性分析。2010年2月至2016年12月，我们对13例发生升主动脉扩张的成年VSD患者（12例男性，占92.31%）进行了手术。中位年龄为37岁（四分位间距14岁）。所有患者均患有膜周部VSD并接受了手术治疗。术后所有患者症状均改善，无死亡发生。手术治疗成年先天性VSD患者的升主动脉扩张是可行的。成功手术需要适当的围手术期治疗及密切监测。
