Tianjin Key Laboratory of Molecular Optoelectronic Science, Department of Chemistry, School of Science, Tianjin University, Tianjin 300072, China.
School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
Sensors (Basel). 2018 Apr 8;18(4):1134. doi: 10.3390/s18041134.
The spatial confinement of conjugated phenyl rotators is a compulsory requirement for the fluorescence enhancement of aggregation induced emission (AIE) molecules. This work reports a novel spatially confined AIE material by restricting several tetraphenylethylene (TPE) molecules around the primary face of β-cyclodextrin (CD) via a Cu(I) catalytic 1,3-dipolar cycloaddition reaction (click chemistry). The spatial confinement effect was found to significantly enhance the fluorescence emission when compared with a single TPE modified CD. In addition, the emission maxima took place with the dimethyl sulfoxide volume ratio of 30% in a water mixture, which is remarkably different from traditional AIE molecules. Benefiting from the CD's complexation effect, this material exhibits a selective fluorescence quenching property in certain hydrogenases and can be used as a fluorescence probe for hydrogenase sensing. This demonstrates the potential of the spatially confined AIECD for practical applications.
共轭苯基旋转体的空间限制是聚集诱导发射（AIE）分子荧光增强的必要条件。本工作通过 Cu(I)催化 1,3-偶极环加成反应（点击化学）将几个四苯乙烯（TPE）分子限制在β-环糊精（CD）的主面上，报道了一种新型的空间受限 AIE 材料。与单个 TPE 修饰的 CD 相比，空间限制效应显著增强了荧光发射。此外，在水混合溶液中，当二甲基亚砜体积比为 30%时，发射最大值发生，这与传统的 AIE 分子显著不同。得益于 CD 的络合效应，该材料在某些氢化酶中表现出选择性荧光猝灭性质，可作为氢化酶传感的荧光探针。这表明空间受限 AIECD 在实际应用中的潜力。
