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加拿大安大略省难民孕产妇和围产期健康:一项基于人群的回顾性研究。

Refugee maternal and perinatal health in Ontario, Canada: a retrospective population-based study.

作者信息

Wanigaratne Susitha, Shakya Yogendra, Gagnon Anita J, Cole Donald C, Rashid Meb, Blake Jennifer, Dastoori Parisa, Moineddin Rahim, Ray Joel G, Urquia Marcelo L

机构信息

Centre for Urban Health Solutions, St. Michael's Hospital, Toronto, Ontario, Canada.

Institute for Clinical Evaluative Sciences, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

出版信息

BMJ Open. 2018 Apr 10;8(4):e018979. doi: 10.1136/bmjopen-2017-018979.

Abstract

OBJECTIVES

Immigrants are thought to be healthier than their native-born counterparts, but less is known about the health of refugees or forced migrants. Previous studies often equate refugee status with immigration status or country of birth (COB) and none have compared refugee to non-refugee immigrants from the same COB. Herein, we examined whether: (1) a refugee mother experiences greater odds of adverse maternal and perinatal health outcomes compared with a similar non-refugee mother from the same COB and (2) refugee and non-refugee immigrants differ from Canadian-born mothers for maternal and perinatal outcomes.

DESIGN

This is a retrospective population-based database study. We implemented two cohort designs: (1) 1:1 matching of refugees to non-refugee immigrants on COB, year and age at arrival (±5 years) and (2) an unmatched design using all data.

SETTING AND PARTICIPANTS

Refugee immigrant mothers (n=34 233), non-refugee immigrant mothers (n=243 439) and Canadian-born mothers (n=615 394) eligible for universal healthcare insurance who had a hospital birth in Ontario, Canada, between 2002 and 2014.

PRIMARY OUTCOMES

Numerous adverse maternal and perinatal health outcomes.

RESULTS

Refugees differed from non-refugee immigrants most notably for HIV, with respective rates of 0.39% and 0.20% and an adjusted OR (AOR) of 1.82 (95% CI 1.19 to 2.79). Other elevated outcomes included caesarean section (AOR 1.04, 95% CI 1.00 to 1.08) and moderate preterm birth (AOR 1.08, 95% CI 0.99 to 1.17). For the majority of outcomes, refugee and non-refugee immigrants experienced similar AORs when compared with Canadian-born mothers.

CONCLUSIONS

Refugee status was associated with a few adverse maternal and perinatal health outcomes, but the associations were not strong except for HIV. The definition of refugee status used herein may not sensitively identify refugees at highest risk. Future research would benefit from further refining refugee status based on migration experiences.

摘要

目的

人们认为移民比在本国出生的人更健康,但对于难民或被迫移民的健康状况了解较少。以往的研究常常将难民身份等同于移民身份或出生国,而且没有研究比较过来自同一出生国的难民与非难民移民。在此,我们研究了:(1)与来自同一出生国的类似非难民母亲相比,难民母亲出现不良孕产妇和围产期健康结局的几率是否更高;(2)难民和非难民移民在孕产妇和围产期结局方面与加拿大出生的母亲有何不同。

设计

这是一项基于人群的回顾性数据库研究。我们采用了两种队列设计:(1)按照出生国、抵达年份和年龄(±5岁)将难民与非难民移民进行1:1匹配;(2)使用所有数据的非匹配设计。

背景与参与者

2002年至2014年期间在加拿大安大略省有医院分娩记录、符合全民医疗保险资格的难民移民母亲(n = 34233)、非难民移民母亲(n = 243439)和加拿大出生的母亲(n = 615394)。

主要结局

众多不良孕产妇和围产期健康结局。

结果

难民与非难民移民在艾滋病毒方面差异最为显著,各自的感染率分别为0.39%和0.20%,调整后的比值比(AOR)为1.82(95%置信区间1.19至2.79)。其他升高的结局包括剖宫产(AOR 1.04,95%置信区间1.00至1.08)和中度早产(AOR 1.08,95%置信区间0.99至1.17)。与加拿大出生的母亲相比,在大多数结局方面,难民和非难民移民的AOR相似。

结论

难民身份与一些不良孕产妇和围产期健康结局相关,但除艾滋病毒外,这些关联并不强烈。本文使用的难民身份定义可能无法敏感地识别出风险最高的难民。未来的研究将受益于根据移民经历进一步完善难民身份定义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a60/5898303/fdd64c1e8716/bmjopen-2017-018979f01.jpg

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