Gupta Abhishek
Geriatrics, Center for Addiction and Mental Health.
Cureus. 2018 Feb 8;10(2):e2174. doi: 10.7759/cureus.2174.
Transcranial magnetic stimulation (rTMS) and sleep deprivation (SD) are two of the latest advances made in the field of psychiatric research. Though yet in development, they present unique opportunities to achieve significant clinical outcomes particularly in major depression disorder (MDD). A limited set of studies have been done in the combined use of rTMS-SD in treating MDD. While promising, these studies have been hampered by the limited knowledge of rTMS and SD themselves due to their relatively recent use as viable therapeutic options. This review is aimed at an analysis of the limitations observed in the studies conducted to date involving rTMS and SD. In addition, it explores the potential new avenues for future research in the deployment of rTMS-SD as a viable treatment option.
经颅磁刺激(rTMS)和睡眠剥夺(SD)是精神科研究领域的两项最新进展。尽管仍在发展中,但它们提供了独特的机会来取得显著的临床效果,尤其是在重度抑郁症(MDD)方面。关于联合使用rTMS-SD治疗MDD的研究较少。尽管这些研究很有前景,但由于rTMS和SD作为可行的治疗选择使用时间相对较短,人们对它们本身的了解有限,这阻碍了这些研究的进展。本综述旨在分析迄今为止涉及rTMS和SD的研究所观察到的局限性。此外,它还探讨了将rTMS-SD作为可行治疗选择进行未来研究的潜在新途径。