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探讨 SSKI 与局部肝素联合治疗游走性结节红斑病例。

Exploring the combination of SSKI and topical heparin in a case of erythema nodosum migrans.

机构信息

Department of Dermatology, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, 110001, India.

出版信息

Dermatol Ther. 2018 Jul;31(4):e12610. doi: 10.1111/dth.12610. Epub 2018 Apr 11.

Abstract

Erythema nodosum migrans (subacute nodular migratory panniculitis) is an uncommon type of panniculitis characterized by migrating subcutaneous nodules or plaque on the lower extremity. There are a very few cases of Erythema nodosum migrans reported and thus its appropriate treatment modality is not defined. We describe a case of a 30-year-old male with idiopathic erythema nodosum migrans which was manifest centrifugally spreading, slightly morpheaform erythematous plaque on the lower left leg. The patient was diagnosed initially and treated as a case of furunculosis with poor clinical response. The skin biopsy showed features consistent with subacute nodular panniculitis. Saturated Solution of Potassium Iodide along with topical Heparin successfully treated the patient, when the conventional treatment modalities failed. In a morpheaform centrifugally expanded plaque, erythema nodosum migrans should be kept in mind in the differential diagnosis, especially in the lower extremities in cases of unknown etiology.

摘要

游走性结节性红斑(亚急性结节性游走性脂膜炎)是一种罕见的脂膜炎类型,其特征为下肢移行性皮下结节或斑块。游走性结节性红斑的报道病例非常少,因此其合适的治疗方式尚未确定。我们描述了一例 30 岁男性的特发性游走性结节性红斑病例,其表现为左小腿离心性扩散的、轻微硬皮病样红斑性斑块。最初诊断为痈,并进行了治疗,但临床反应不佳。皮肤活检显示符合亚急性结节性脂膜炎的特征。当常规治疗方法失败时,饱和碘化钾溶液联合肝素局部治疗成功治愈了该患者。在硬皮病样离心性扩张斑块中,游走性结节性红斑应在鉴别诊断中加以考虑,特别是在下肢不明原因的情况下。

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