Morikawa T, Yamadori I, Hirakawa E, Okino T, Kobayashi S, Ohmori M
Dept. of Pathology, Kagawa Medical School.
Gan No Rinsho. 1988 Feb;34(2):196-200.
Two cases of an IBL-like T-cell lymphoma are reported, in one case of which the histological changes could be observed throughout its course. Although both cases were difficult to differentiate from true IBL in their early stage, focal proliferation of pale cells appeared in their first specimens and gradually, the characteristics of lymphoma grew manifest. Immunohistochemical studies of both cases revealed lymphoma cells having the characteristics of helper/inducer T lymphocytes. Electron-Microscopic examination showed no particular differences in the morphology of the tumor cells between our case and the case previously reported as being an IBL-like T-cell lymphoma of a suppressor/cytotoxic character.
报告了2例原发性皮肤间变性大细胞淋巴瘤样T细胞淋巴瘤，其中1例在其病程中可观察到组织学变化。尽管两例在早期均难以与真性原发性皮肤间变性大细胞淋巴瘤区分，但在其首次标本中出现了淡染细胞的局灶性增殖，并且淋巴瘤的特征逐渐变得明显。两例的免疫组织化学研究显示淋巴瘤细胞具有辅助/诱导性T淋巴细胞的特征。电子显微镜检查显示，我们的病例与先前报道的具有抑制/细胞毒性特征的原发性皮肤间变性大细胞淋巴瘤样T细胞淋巴瘤病例之间，肿瘤细胞形态没有特别差异。
