Djerić Dragoslava, Folić Miljan, Janićijević Miloš, Blažić Srbislav, Popadić Danka
Srp Arh Celok Lek. 2016 May-Jun;144(5-6):315-9.
Necrotizing otitis externa is a rare but conditionally fatal infection of external auditory canal with extension to deep soft tissue and bones, resulting in necrosis and osteomyelitis of the temporal bone and scull base. This condition is also known as malignant otitis due to an aggressive behavior and poor treatment response. Early diagnosis of malignant otitis is a difficult challenge. We present an illustrative case of necrotizing otitis externa and suggest some strategies to avoid diagnostic and treatment pitfalls.
A 70-year-old patient presented with signs of malignant otitis externa, complicated by peripheral facial palsy. Adequate diagnostic and treatment procedures were performed with clinical signs of resolution. The recurrence of malignant infection had presented three months after previous infection with multiple cranial nerve neuropathies and signs of jugular vein and lateral sinus thrombosis. An aggressive antibiotic treatment and surgery were carried out, followed by substantial recovery of the patient and complete restoration of cranial nerves’ functions.
Necrotizing otitis externa is a serious condition with uncertain prognosis. The suspicion of malignant external otitis should be raised in cases of resistance to topical treatment, especially in patient with predisposing factors. Evidence-based guideline for necrotizing otitis externa still doesn’t exist and treatment protocol should be adjusted to individual presentation of each patient.
坏死性外耳道炎是一种罕见但可能致命的外耳道感染,可蔓延至深部软组织和骨骼,导致颞骨和颅底坏死及骨髓炎。由于其侵袭性和治疗反应不佳,这种疾病也被称为恶性外耳道炎。早期诊断恶性外耳道炎是一项艰巨的挑战。我们展示了一例坏死性外耳道炎的病例,并提出了一些避免诊断和治疗陷阱的策略。
一名70岁患者出现恶性外耳道炎症状,并伴有周围性面瘫。通过适当的诊断和治疗程序,临床症状得到缓解。在先前感染三个月后,恶性感染复发,出现多发性颅神经病变以及颈静脉和外侧窦血栓形成的迹象。进行了积极的抗生素治疗和手术,随后患者大幅康复,颅神经功能完全恢复。
坏死性外耳道炎是一种预后不确定的严重疾病。对于局部治疗无效的病例,尤其是有易感因素的患者,应怀疑恶性外耳道炎。目前仍不存在基于证据的坏死性外耳道炎指南,治疗方案应根据每个患者的个体表现进行调整。