Szaluś-Jordanow Olga, Czopowicz Michał, Witkowski Lucjan, Moroz Agata, Mickiewicz Marcin, Frymus Tadeusz, Markowska-Daniel Iwona, Bagnicka Emilia, Kaba Jarosław
Department of Small Animal Diseases with Clinic, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159c, 02-776 Warsaw, Poland.
Laboratory of Veterinary Epidemiology and Economics, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159c, 02-776 Warsaw, Poland.
Res Vet Sci. 2018 Jun;118:351-356. doi: 10.1016/j.rvsc.2018.03.005. Epub 2018 Mar 8.
The study aimed to evaluate the effect of pregnancy on heart diameters and function in goats. Transthoracic echocardiography of 12 female dairy goats of two Polish regional breeds was performed. A Mindray M7 diagnostic ultrasound system with Phased Array transducer was used. Simultaneously, electrocardiography was recorded. All animals were examined four times - at mating season, at the end of the first trimester, at the end of the second trimester and just before kidding. Eleven measurements were taken each time: aortic and left atrial diameter (AoD and LAD), right and left ventricular internal diameter in diastole (RVIDd and LVIDd), left ventricular internal diameter in systole (LVIDs), inter-ventricular septum thickness in diastole and systole (IVSd and IVSd) and left ventricular posterior wall in diastole and systole (LVPWd and LVPWs), maximum left and right ventricular outflow tract velocity (RVOT Vmax and LVOT Vmax). Nine consecutive measurements were derived: the ratio of the left atrial diameter to the aortic diameter (AoD/LAD), left ventricular fractional shortening (FS%), left ventricular ejection fraction (EF%), maximum outflow tract pressure gradients (RVOT PGmax and LVOT PGmax), left ventricular end-diastolic volume (LVEDV) and left ventricular end-systolic volume (LVESV), stroke volume (SV) and cardiac output (CO). HR, LAD, LVPWs, IVSs increased significantly in the first trimester. AoD and RVIDd were significantly higher around parturition. LVIDd, FS%, EF%, SV and CO rose both in the first and third trimester. No measurement decreased during pregnancy. The study confirms that pregnancy causes changes in the heart size and functioning.
该研究旨在评估妊娠对山羊心脏直径和功能的影响。对两个波兰地方品种的12只雌性奶山羊进行了经胸超声心动图检查。使用了配备相控阵探头的迈瑞M7诊断超声系统。同时，记录心电图。所有动物在四个时间点接受检查——交配季节、孕早期结束时、孕中期结束时和即将分娩前。每次进行11项测量：主动脉和左心房直径（AoD和LAD）、舒张期右心室和左心室内径（RVIDd和LVIDd）、收缩期左心室内径（LVIDs）、舒张期和收缩期室间隔厚度（IVSd和IVSd）以及舒张期和收缩期左心室后壁厚度（LVPWd和LVPWs）、左右心室流出道最大速度（RVOT Vmax和LVOT Vmax）。得出9个连续测量值：左心房直径与主动脉直径之比（AoD/LAD）、左心室缩短分数（FS%）、左心室射血分数（EF%）、最大流出道压力梯度（RVOT PGmax和LVOT PGmax）、左心室舒张末期容积（LVEDV）和左心室收缩末期容积（LVESV）、每搏输出量（SV）和心输出量（CO）。孕早期HR、LAD、LVPWs、IVSs显著增加。分娩前后AoD和RVIDd显著更高。LVIDd、FS%、EF%、SV和CO在孕早期和孕晚期均升高。孕期没有测量值下降。该研究证实妊娠会导致心脏大小和功能发生变化。
