Klinik für Anästhesiologie, Universitätsklinikum Regensburg, Regensburg, Deutschland.
Medizinische Klinik II, Intensivmedizin, Universitätsklinikum Regensburg, Regensburg, Deutschland.
PLoS One. 2018 Apr 13;13(4):e0193558. doi: 10.1371/journal.pone.0193558. eCollection 2018.
Transcatheter aortic valve implantation (TAVI) is a minimally invasive procedure used to treat degenerative heart valve disease. The implantation requires a highly specific and interdisciplinary management approach. Currently, TAVI is performed with the patient under local or general anaesthesia.
This study was a retrospective analysis of all TAVI procedures performed at the University Hospital of Regensburg between January 2009 and July 2015. All pre-, intra and postoperative data focusing on perioperative complications were recorded.
A total of 853 transfemoral- and transapical-TAVI patients were included in the study. All patients underwent general anaesthesia. The ASA classifications were primarily 3-4. The average logistic EuroScores for the transfemoral- and transapical-TAVI patients were 18 ± 12% and 21 ± 15% (p = 0.002), respectively. The anaesthesia coverage time was 170 ± 49 min., including 37 ± 12 minutes for anaesthetic management. Overall, 458 complications were recorded; with pneumonia, acute renal failure, indication for a permanent pacemaker and non-extubation in the operating theatre the most frequently recorded complications.
In the present study, we showed that our patients' outcomes are comparable to those reported in the available literature. Compared to TF, TA patients show an overall worse physical condition as well as a higher perioperative morbidity and mortality. Consequently TA patients need additional care and should only be operated in appropriately experienced medical centres.
经导管主动脉瓣植入术(TAVI)是一种用于治疗退行性心脏瓣膜病的微创程序。该植入术需要高度专业和跨学科的管理方法。目前,TAVI 是在局部或全身麻醉下进行的。
本研究回顾性分析了 2009 年 1 月至 2015 年 7 月期间在雷根斯堡大学医院进行的所有 TAVI 手术。所有关注围手术期并发症的术前、术中及术后数据均被记录。
共有 853 例经股动脉和经心尖 TAVI 患者纳入研究。所有患者均接受全身麻醉。ASA 分级主要为 3-4 级。经股动脉和经心尖 TAVI 患者的平均逻辑 EuroScores 分别为 18 ± 12%和 21 ± 15%(p = 0.002)。麻醉覆盖时间为 170 ± 49 分钟,其中 37 ± 12 分钟用于麻醉管理。总的来说,记录了 458 例并发症;最常见的并发症是肺炎、急性肾衰竭、需要永久性起搏器和手术室非拔管。
在本研究中,我们表明我们患者的结果与现有文献报告的结果相当。与 TF 相比,TA 患者的整体身体状况较差,围手术期发病率和死亡率较高。因此,TA 患者需要额外的护理,只能在有经验的医疗中心进行手术。