Chang Chin-Fang, Hsieh Ming-Yu, Chen Mu-Kuan, Chou Ming-Chih
Institute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan; Department of Otorhinolaryngology, Head and Neck Surgery, Jen-Ai Hospital, Taichung 400, Taiwan; Central Taiwan University of Science and Technology, Taichung, Taiwan.
Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, Changhua, Taiwan.
Auris Nasus Larynx. 2018 Aug;45(4):831-837. doi: 10.1016/j.anl.2017.10.009. Epub 2018 Apr 10.
In this study, patients with head and neck adenoid cystic carcinoma were investigated with respect to disease characteristics, treatments, and potentially prognostic variables.
Between January 1995 and December 2010, 29 patients with ACC of the head and neck treated at our institution were retrospectively reviewed.
The 29 patients had a mean age of 54.7 years. Of the 29 patients, 4 (13.8%) underwent surgical resection only, 21 (72.4%) underwent surgery with radiotherapy, and 4 (13.8%) received postoperative chemoradiotherapy. Of 9 patients (31.0%) who experienced a recurrence within the follow-up period, 3 (10.3%) had local recurrence and 5 (17.2%) had distant metastasis; 1 (3.4%) patient had both local recurrence and distant metastatic spread.
ACC is a relatively rare tumor associated with long survival, even in metastatic settings. Despite aggressive therapy with surgery, radiotherapy, and chemo- therapy, a marked potential for local and distant recurrence still remains.
在本研究中，对患有头颈部腺样囊性癌的患者的疾病特征、治疗方法及潜在的预后变量进行了调查。
回顾性分析了1995年1月至2010年12月期间在我院接受治疗的29例头颈部腺样囊性癌患者。
29例患者的平均年龄为54.7岁。29例患者中，4例（13.8%）仅接受了手术切除，21例（72.4%）接受了手术加放疗，4例（13.8%）接受了术后放化疗。在随访期间出现复发的9例患者（31.0%）中，3例（10.3%）为局部复发，5例（17.2%）发生远处转移；1例（3.4%）患者同时出现局部复发和远处转移。
腺样囊性癌是一种相对罕见的肿瘤，即使在发生转移的情况下患者仍可长期存活。尽管采用了手术、放疗和化疗等积极的治疗方法，但局部和远处复发的可能性仍然很大。
