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[血管成形术中冠状动脉内血流速度。扩张成功的功能导向及指标]

[Intracoronary blood flow velocity during angioplasty. Functional guide and indicator of the success of dilatation].

作者信息

Juillière Y, Zijlstra F, de Feyter P, Suryapranata H, Serruys P W

机构信息

Thoraxcenter, Erasmus University, Rotterdam, The Netherlands.

出版信息

Arch Mal Coeur Vaiss. 1987 Nov;80(12):1725-33.

PMID:2965559
Abstract

In order to assess the value of a new Doppler-fitted dilatation catheter, changes in blood flow velocities in the coronary arteries were recorded at various stages of transluminal angioplasty in 15 patients with isolated proximal coronary stenosis. A pulsed Doppler probe (emission frequency 20 MHz, recurrence frequency 62.5 MHz) attached to the distal end of the balloon catheter was used to measure blood flow velocities with a Doppler frequency/velocity relationship of about 3.75 cm/s per KHz. During each angioplasty the balloon was inflated 4 times on average, with successive increases of pressure from 7 to 12 atmospheres. Flow velocities were measured before and after each inflation and also when maximum hyperaemia occurred after temporary occlusion by the inflated balloon. Computer-assisted analysis of the coronary stenosis was carried out before and after the procedure. Patient's mean age was 53 years. Angioplasty was performed in the anterior interventricular artery (12 cases), the circumflex artery (2 cases) or the right coronary artery (1 case). Anatomical success was assessed by an increase of minimum luminal section area from 1.3 +/- 0.0 to 3.0 +/- 1.2 mm2. Functional success was assessed by a progressive and significant increase of the velocities measured during the first 3 dilatations. No further increase of velocity was observed between the last 2 inflations. Coronary reserve at the end of angioplasty was 2.1, corresponding to the theoretical value calculated taking into account the residual stenosis and the presence of the catheter in situ.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为评估一种新型配备多普勒的扩张导管的价值,对15例孤立性近端冠状动脉狭窄患者在经皮腔内血管成形术的不同阶段记录冠状动脉内的血流速度变化。将一个脉冲多普勒探头(发射频率20MHz,重复频率62.5MHz)连接到球囊导管的远端,用于测量血流速度,其多普勒频率/速度关系约为每千赫兹3.75厘米/秒。在每次血管成形术中,球囊平均充气4次,压力从7个大气压依次增加到12个大气压。在每次充气前后以及球囊充气暂时阻断后出现最大充血时测量血流速度。在手术前后对冠状动脉狭窄进行计算机辅助分析。患者的平均年龄为53岁。血管成形术在前降支动脉(12例)、回旋支动脉(2例)或右冠状动脉(1例)中进行。解剖学成功的评估标准是最小管腔截面积从1.3±0.0增加到3.0±1.2平方毫米。功能成功的评估标准是在前3次扩张过程中测量的速度逐渐且显著增加。在最后2次充气之间未观察到速度进一步增加。血管成形术结束时的冠状动脉储备为2.1,与考虑残余狭窄和导管原位存在情况计算出的理论值相对应。(摘要截断于250字)

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