Perez T, Cattan S, Weber S, Fouchard J, Guérin F, Degeorges M
Service de cardiologie, Université René Descartes, Hôpital Cochin, Paris.
Arch Mal Coeur Vaiss. 1987 Dec;80 Spec No:51-6.
The presence of ischaemic myocardial tissues in necrotic territories and the usefulness of revascularizing these territories are controversial matters. We have determined the existence of this phenomenon by the per-angioplastic intracoronary ECG method, and we have compared the sensitivities of intracoronary ECG and surface ECG. Intracoronary EVG is achieved by using the mobile teflon-coated guide wire of coronary angioplasty as a unipolar epicardial electrode. Being epicardial and localized, the electrode explores a limited area of the myocardium, distal to the artery being dilated and momentarily occluded by the balloon during inflations. The study involved 12 patients (mean age 53.7 years) who presented with the following criteria of admission: transmural myocardial infarction, presence of a Q wave on two leads, akinetic segment at ventriculography and coronary stenosis or occlusion amenable to angioplasty. Patients with collateral circulation between the larger epicardial vessels were excluded. Intracoronary ECG recordings were taken before, during and after inflations. In 9 out of 12 patients the ST segments was elevated by 1.3 mV on average between inflations (S.D. 3.14 mV) and by 4.8 mV (S.D. 3.99 mV) during inflations. These high standard deviations were due to major inter- and intra-individual variations of ST. The difference was significant (p less than 0.05) at variance analysis. No variation of ST was observed in 3 patients. Only one of the 12 patients had elevated ST on both surface ECG and intracoronary ECG tracings. Thus, intracoronary ECG is a sensitive method to evaluate myocardial ischaemia during coronary angioplasty.(ABSTRACT TRUNCATED AT 250 WORDS)
梗死区域缺血性心肌组织的存在以及对这些区域进行血运重建的有效性是存在争议的问题。我们通过血管成形术时冠状动脉内心电图方法确定了这种现象的存在,并且比较了冠状动脉内心电图和体表心电图的敏感性。冠状动脉内心电图是通过使用冠状动脉成形术的可移动聚四氟乙烯涂层导丝作为单极心外膜电极来实现的。该电极位于心外膜且位置局限,可探测心肌的有限区域,该区域在动脉扩张且球囊充气时暂时阻塞的动脉远端。该研究纳入了12例患者(平均年龄53.7岁),入选标准如下:透壁性心肌梗死,两个导联出现Q波,心室造影显示运动减弱节段,以及适合进行血管成形术的冠状动脉狭窄或闭塞。排除大的心外膜血管之间存在侧支循环的患者。在充气前、充气期间和充气后进行冠状动脉内心电图记录。12例患者中有9例在充气期间ST段平均升高1.3 mV(标准差3.14 mV),充气时升高4.8 mV(标准差3.99 mV)。这些高标准差是由于ST段在个体间和个体内存在较大差异。方差分析显示差异具有统计学意义(p<0.05)。3例患者未观察到ST段变化。12例患者中只有1例在体表心电图和冠状动脉内心电图记录上均出现ST段升高。因此,冠状动脉内心电图是评估冠状动脉成形术期间心肌缺血的一种敏感方法。(摘要截取自250字)