Department of Biopharmaceutics and Pharmacodynamics, Medical University of Gdańsk, Hallera 107, 30-216, Gdańsk, Poland.
Department of Biopharmaceutics and Pharmacodynamics, Medical University of Gdańsk, Hallera 107, 30-216, Gdańsk, Poland.
J Chromatogr A. 2018 Jul 20;1559:17-43. doi: 10.1016/j.chroma.2018.04.002. Epub 2018 Apr 7.
In this review, we will firstly discuss the types and the general properties of silica, focusing on the silica support used in chromatography and capillary electrophoresis. Additionally, the characterization of functional groups (silanols and siloxanes) will be considered in terms of activity of the stationary phases. We will then discuss physical chemistry of the stationary phases applied in liquid chromatography and capillary electrophoresis. The use of ionic liquids as a silanols' suppressors will be presented in the next parts of the study, along with the examples of specific applications. The review is completed with conclusions and an outlook for the future developments in the area of analytical applications of ionic liquids.
在这篇综述中，我们首先将讨论二氧化硅的类型和一般性质，重点是用于色谱法和毛细管电泳的二氧化硅载体。此外，我们还将从固定相的活性角度考虑官能团（硅醇和硅氧烷）的特性。然后，我们将讨论应用于液相色谱法和毛细管电泳的固定相的物理化学。在研究的下一部分，我们将介绍离子液体作为硅醇抑制剂的应用，并举例说明具体应用。最后，我们将对离子液体在分析应用领域的未来发展进行总结和展望。
