Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University School of Medicine, New York, New York.
Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York.
Magn Reson Med. 2018 Nov;80(5):1935-1948. doi: 10.1002/mrm.27200. Epub 2018 Apr 15.
Most clinical MR examinations require acquisition of different image contrasts. For abdominal exams, the scans are conventionally performed as separate acquisitions using respiratory gating or repeated breath holding, which can be time-inefficient and challenging for patients. Here, a hybrid imaging approach is described that creates T - and T -weighted images from a single scan and allows for free-breathing acquisition.
T -weighted data is collected using 3D fast spin-echo (FSE) acquisition with motion-robust radial stack-of-stars sampling. The wait time between the FSE trains is used to acquire T -weighted gradient-echo (GRE) data. Improved robustness is achieved by extracting a respiratory signal from the GRE data and using it for motion-weighted reconstruction.
As validated in simulations and phantom scans, GRE acquisition in the wait time has minor effect on the signal strength and contrast. Volunteer scans at 1.5T showed that T - and T -weighted hybrid imaging is feasible during free-breathing. Furthermore, it has been demonstrated in a patient that hybrid imaging with T -weighted Dixon acquisition is possible.
The described hybrid sequence enables comprehensive T - and T -weighted imaging in a single scan. In addition to free-breathing abdominal examination, it promises value for clinical applications that are frequently affected by motion artifacts.
大多数临床磁共振检查需要获取不同的图像对比。对于腹部检查,扫描通常使用呼吸门控或重复屏气作为单独的采集来进行,这可能效率低下,对患者也具有挑战性。本文描述了一种混合成像方法,可从单次扫描中创建 T1 和 T2 加权图像,并允许自由呼吸采集。
使用具有运动稳健性的径向星形堆栈采集的 3D 快速自旋回波(FSE)采集来采集 T1 加权数据。在 FSE 列车之间的等待时间用于采集 T2 加权梯度回波(GRE)数据。通过从 GRE 数据中提取呼吸信号并将其用于运动加权重建,可以提高稳健性。
在模拟和体模扫描中进行验证,等待时间内的 GRE 采集对信号强度和对比度的影响较小。在 1.5T 志愿者扫描中,表明在自由呼吸期间可以进行 T1 和 T2 加权的混合成像。此外,在一名患者中证明了 T 加权 Dixon 采集的混合成像也是可行的。
所描述的混合序列可在单次扫描中实现全面的 T1 和 T2 加权成像。除了自由呼吸的腹部检查外,它还可为经常受到运动伪影影响的临床应用带来价值。