From the National Institute on Drug Abuse, Bethesda, Md.; and the Substance Abuse and Mental Health Services Administration, Rockville, Md.
Am J Psychiatry. 2018 Aug 1;175(8):741-755. doi: 10.1176/appi.ajp.2018.17091048. Epub 2018 Apr 16.
The authors sought to simultaneously examine the prevalence and correlates of prescription stimulant use, misuse, use disorders, and motivations for misuse in the U.S. adult population.
This was a nationally representative household population study of adults age 18 or older from the 2015 and 2016 National Surveys on Drug Use and Health (N=102,000). Measurements included prescription stimulant use, use without misuse, misuse without use disorders, and misuse with use disorders, as well as sociodemographic characteristics, health conditions, and mental health factors.
Among U.S. adults, 6.6% (annual average) used prescription stimulants overall; 4.5% used without misuse, 1.9% misused without use disorders, and 0.2% had use disorders. Adults with past-year prescription stimulant use disorders did not differ from those with misuse without use disorders in any of the examined sociodemographic characteristics and in many of the examined substance use problems. The most commonly reported motivations for misuse were to help be alert or concentrate (56.3%). The most likely source of misused prescription stimulants was by obtaining them free from friends or relatives (56.9%). More frequent prescription stimulant misuse and use disorder were associated with an increased likelihood of obtaining medications from physicians or from drug dealers or strangers and less likelihood of obtaining them from friends or relatives.
Approximately 16.0 million U.S. adults used prescription stimulants in the preceding year (annual average), 5.0 million misused prescription stimulants, and 0.4 million had use disorders. Cognitive enhancement was the most commonly reported reason for misusing prescription stimulants. Patients who are using their medication for cognitive enhancement or diverting their medication to others present a high risk.
作者旨在同时考察美国成年人群中处方兴奋剂的使用、滥用、使用障碍以及滥用动机的流行情况和相关因素。
这是一项针对年龄在 18 岁及以上的成年人的全国代表性家庭人群研究,来自 2015 年和 2016 年国家药物使用与健康调查(N=102000)。测量包括处方兴奋剂的使用、无滥用使用、无使用障碍滥用和有使用障碍滥用,以及社会人口统计学特征、健康状况和心理健康因素。
在美国成年人中,6.6%(年平均)总体上使用处方兴奋剂;4.5%无滥用使用,1.9%滥用无使用障碍,0.2%有使用障碍。过去一年有处方兴奋剂使用障碍的成年人在任何被检查的社会人口统计学特征和许多被检查的物质使用问题上与无使用障碍滥用的成年人没有区别。最常报告的滥用动机是帮助保持警觉或集中注意力(56.3%)。最常见的误用处方兴奋剂来源是从朋友或亲戚那里免费获得(56.9%)。更频繁的处方兴奋剂滥用和使用障碍与从医生或毒贩或陌生人获得药物的可能性增加以及从朋友或亲戚获得药物的可能性降低相关。
大约有 1600 万美国成年人在过去一年中使用过处方兴奋剂(年平均),500 万人滥用过处方兴奋剂,0.4 万人有使用障碍。认知增强是最常报告的滥用处方兴奋剂的原因。那些为认知增强而使用药物或将药物转用于他人的患者存在很高的风险。