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学生药剂师中处方阿片类药物和兴奋剂的非医疗用途。

Nonmedical use of prescription opioids and stimulants among student pharmacists.

作者信息

Lord Sarah, Downs George, Furtaw Paul, Chaudhuri Anamika, Silverstein Amy, Gammaitoni Arnold, Budman Simon

机构信息

National Development and Research Institutes, Inc, New York, USA.

出版信息

J Am Pharm Assoc (2003). 2009 Jul-Aug;49(4):519-28. doi: 10.1331/JAPhA.2009.08027.

Abstract

OBJECTIVES

To examine the prevalence and patterns of nonmedical use of prescription opioid analgesics and stimulants among student pharmacists.

DESIGN

Descriptive, nonexperimental, cross-sectional study.

SETTING

Private urban college of pharmacy in the United States in fall 2006.

PARTICIPANTS

1,538 PharmD students.

INTERVENTION

Online survey.

MAIN OUTCOME MEASURES

Lifetime and past-year nonmedical prescription opioid and stimulant use.

RESULTS

Response rate for the survey was 62%. Lifetime prevalence of opioid misuse was 8%, and 5% of students had misused in the past year. Lifetime prevalence of stimulant misuse was 7%, and 5% had misused in the past year. Whites and fraternity or sorority members were more likely than their peers to have ever misused opioids. Past-year opioid misuse was more likely among whites, men, and low academic achievers compared with their peers. Lifetime stimulant misuse was more likely among students who were white, older, and fraternity or sorority members, while past-year misuse was more likely among whites and low academic achievers. Common motives for opioid misuse were to have fun, to relax, and to deal with chronic pain. Stimulants were used to improve concentration and academic performance. Friends were the most common source of prescription opioids and stimulants. Nonmedical prescription use was associated with greater likelihood of alcohol and other illicit substance use.

CONCLUSION

The prevalence of prescription medication misuse among student pharmacists was lower than (opioids) or comparable with (stimulants) reported rates in college populations. Subgroups of students demonstrated higher rates of nonmedical use, including whites, students involved with fraternities or sororities, and low academic achievers. That friends were the primary source of misused medications indicates that diversion of prescription-only controlled substances likely occurs among student pharmacists. Nonmedical prescription medication use should be considered in the context of other substance use.

摘要

目的

调查药学专业学生中处方类阿片类镇痛药和兴奋剂非医疗用途的流行情况及模式。

设计

描述性、非实验性横断面研究。

地点

2006年秋季美国一所私立城市药学院。

参与者

1538名药学博士学生。

干预措施

在线调查。

主要观察指标

终生及过去一年中处方类阿片类药物和兴奋剂的非医疗用途。

结果

调查的回复率为62%。阿片类药物滥用的终生患病率为8%,过去一年中有5%的学生有过滥用行为。兴奋剂滥用的终生患病率为7%,过去一年中有5%的学生有过滥用行为。白人和兄弟会或姐妹会成员比同龄人更有可能曾滥用阿片类药物。与同龄人相比,过去一年中,白人、男性和学业成绩差的学生更有可能滥用阿片类药物。终生兴奋剂滥用在白人、年龄较大的学生以及兄弟会或姐妹会成员中更为常见,而过去一年的滥用在白人和学业成绩差的学生中更为常见。阿片类药物滥用的常见动机是娱乐、放松和应对慢性疼痛。使用兴奋剂是为了提高注意力和学习成绩。朋友是处方类阿片类药物和兴奋剂最常见的来源。非医疗处方用药与酒精和其他非法药物使用的可能性更大有关。

结论

药学专业学生中处方药滥用的患病率低于(阿片类药物)或与(兴奋剂)大学人群报告的患病率相当。学生亚组中非医疗用途的发生率较高,包括白人、参与兄弟会或姐妹会的学生以及学业成绩差的学生。朋友是滥用药物的主要来源,这表明仅用于处方的管制物质可能在药学专业学生中存在转移现象。非医疗处方用药应结合其他物质使用情况来考虑。

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