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腔内冠状动脉再灌注导管:一种在冠状动脉血管成形术失败与急诊冠状动脉搭桥手术之间维持冠状动脉灌注的装置。

Transluminal intracoronary reperfusion catheter: a device to maintain coronary perfusion between failed coronary angioplasty and emergency coronary bypass surgery.

作者信息

Hinohara T, Simpson J B, Phillips H R, Stack R S

机构信息

Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.

出版信息

J Am Coll Cardiol. 1988 May;11(5):977-82. doi: 10.1016/s0735-1097(98)90054-7.

Abstract

The reperfusion catheter is a 4.3F catheter with 30 holes over its distal 10 cm. It is used to maintain coronary blood flow in patients awaiting emergency coronary bypass surgery after failed coronary angioplasty. The insertion of the reperfusion catheter was attempted in 20 patients (14 with total occlusion and 6 with severe residual stenosis judged to be in jeopardy of reclosure before operation). The reperfusion catheter was successfully placed across the obstruction in 18 patients (90%). After successful insertion of the reperfusion catheter, 16 patients had good anterograde flow (Thrombolysis in Myocardial Infaction [TIMI] trial grade II or III); angiographic improvement was associated with significant lessening of ST segment elevation as well as a decrease in chest pain in most patients. Two patients had poor or absent anterograde flow (TIMI grade O or I) because of extensive preexisting intracoronary thrombosis; one died from refractory ventricular fibrillation. In each of the remaining patients emergency coronary bypass surgery was performed with no deaths or significant cardiac complications. The reperfusion catheter is a safe and effective method to reestablish and maintain coronary blood flow before coronary bypass surgery after failed coronary angioplasty. Because there is the potential risk of serious complications, particularly thrombus formation within this catheter, the reperfusion catheter should be used cautiously and the patient should undergo immediate bypass surgery.

摘要

再灌注导管是一种4.3F的导管,在其远端10厘米范围内有30个孔。它用于在冠状动脉血管成形术失败后等待紧急冠状动脉搭桥手术的患者中维持冠状动脉血流。对20例患者尝试插入再灌注导管(14例完全闭塞,6例严重残余狭窄,判断在手术前有再次闭塞的风险)。18例患者(90%)的再灌注导管成功穿过阻塞部位。成功插入再灌注导管后,16例患者有良好的顺行血流(心肌梗死溶栓治疗[TIMI]试验II级或III级);血管造影改善与大多数患者ST段抬高明显减轻以及胸痛减轻相关。2例患者因冠状动脉内已有广泛血栓形成而顺行血流差或无顺行血流(TIMI O级或I级);1例死于难治性室颤。其余患者均接受了紧急冠状动脉搭桥手术,无死亡或严重心脏并发症。再灌注导管是冠状动脉血管成形术失败后在冠状动脉搭桥手术前重建和维持冠状动脉血流的一种安全有效的方法。由于存在严重并发症的潜在风险,特别是该导管内形成血栓,再灌注导管应谨慎使用,患者应立即接受搭桥手术。

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