乙醇提取物对H37Rv的抗分枝杆菌活性评估。
Evaluation of antimycobacterial activity of ethanolic extract against H37Rv .
作者信息
Sudjarwo S A
机构信息
Study Program of Environmental Health, Polytechnic of Health, Surabaya, Indonesia.
Department of Pharmacology, Faculty of Medicine, Wijaya Kusuma University, Surabaya, Indonesia.
出版信息
Vet World. 2018 Mar;11(3):368-372. doi: 10.14202/vetworld.2018.368-372. Epub 2018 Mar 27.
AIM
The aim of this study was to evaluate the antimycobacterial activity of the ethanolic extract .
MATERIALS AND METHODS
Ethanolic extract of was set by maceration method. The broth microdilution and disc diffusion method were used to determine the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC), respectively, of ethanol extract on strain H37Rv.
RESULTS
ethanol extract was found to have the antimycobacterial effects with a MIC value of 1600 μg/ml while MBC value of 3200 μg/ml for H37Rv.
CONCLUSION
From these findings , it can be concluded that a ethanol extract have an antibacterial activity against s H37Rv o and its potency elevated by increasing the a ethanol extract concentration.
目的
本研究旨在评估乙醇提取物的抗分枝杆菌活性。
材料与方法
采用浸渍法制备乙醇提取物。分别采用肉汤微量稀释法和纸片扩散法测定乙醇提取物对H37Rv菌株的最低抑菌浓度（MIC）和最低杀菌浓度（MBC）。
结果
发现乙醇提取物具有抗分枝杆菌作用，对H37Rv的MIC值为1600μg/ml，MBC值为3200μg/ml。
结论
从这些发现可以得出结论，乙醇提取物对H37Rv具有抗菌活性，并且通过提高乙醇提取物浓度其效力增强。
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