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并发乳突蜂窝织炎和朗格汉斯细胞组织细胞增多症:一项具有挑战性的诊断。

Concurrent Mastoid Cellulitis and Langerhans Cells Histiocytosis: 
A Challenging Diagnosis.

作者信息

Ong Hui Yan, Goh Liang Chye, Santhi Kalimuthu, Sha'ariyah Mohamad Mokhtar

机构信息

Department of Otorhinolaryngology, Tengku Ampuan Rahimah Hospital, Klang, Selangor, Malaysia.

Department of Otorhinolaryngology, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

Oman Med J. 2018 Mar;33(2):167-170. doi: 10.5001/omj.2018.31.

Abstract

Langerhans cell histiocytosis (LCH) is a rare proliferative disorder, which commonly arises in the bone and may involve other systems. To date, the diagnosis of temporal bone LCH remains a challenge as it may masquerade as a common ear infection. We report a case of a child who presented to us with persistent bilateral ear discharge for four months and was not responding to treatment. Her condition subsequently worsened, with clinical features and radiological findings suggestive of mastoid cellulitis. Nevertheless, further histopathology study revealed LCH.

摘要

朗格汉斯细胞组织细胞增多症(LCH)是一种罕见的增殖性疾病,通常发生于骨骼,也可能累及其他系统。迄今为止,颞骨LCH的诊断仍然是一项挑战,因为它可能表现为常见的耳部感染。我们报告一例患儿,其双侧耳部持续流脓4个月,治疗无效。随后其病情恶化,临床特征和影像学表现提示乳突蜂窝织炎。然而,进一步的组织病理学研究显示为LCH。

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[Early start eosinophilic granuloma of the temporal bone].[颞骨早期嗜酸性肉芽肿]
Acta Otorrinolaringol Esp. 2010 Jul-Aug;61(4):315-7. doi: 10.1016/j.otorri.2009.05.012.

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