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[中药熏蒸联合左氧氟沙星治疗湿热瘀阻型ⅢA 前列腺炎]

[Traditional Chinese medicine fumigation combined with Levofloxacin for type ⅢA prostatitis with the symptoms of damp heat and blood stasis].

作者信息

Yany Xing-Zhi, Guo Yu, Xiong Wei, Li Jie, Chang De-Gui, Zhang Pei-Hai, Wang You, Wang Xi, Dai Xiao-Hong

机构信息

Department of Urology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400021, China.

Department of Endocrinology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400021, China.

出版信息

Zhonghua Nan Ke Xue. 2017 Feb;23(2):173-177.

Abstract

OBJECTIVE

To investigate the clinical effects of traditional Chinese medicine (TCM) fumigation on type ⅢA prostatitis with the symptoms of damp heat and blood stasis.

METHODS

We randomly divided 72 cases of type ⅢA prostatitis with the symptoms of damp heat and blood stasis into an experimental and a control group of equal number, the former treated with TCM fumigation plus oral Levofloxacin while the latter with oral Levofloxacin only. After 4 weeks of treatment, we compared the National Institute of Health Chronic Prostatitis Symptom Index (NIHCPSI) score, TCM symptoms score, maxinum flow rate (Qmax), and average urinary flow rate (Qave) between the two groups of patients.

RESULTS

The total effectiveness rate was significantly higher in the experimental than in the control group (91.7% vs 61.1%, P< 0.01), while the NIHCPSI score in the experimental group was markedly decreased after treatment as compared with the baseline (14.5 ± 8.2 vs 26.5 ± 9.3, P< 0.05) and significantly lower than that in the control (14.5 ± 8.2 vs 20.6 ± 7.9, P< 0.05). Qmax was remarkably increased in the experimental group after treatment in comparison with the baseline ([21.2 ± 4.3] vs [15.8 ± 3.6] ml/s, P< 0.05) and the control group, and so was Qave as compared with pretreatment ([16.3 ± 3.5] vs [10.5 ± 2.8] ml/s, P< 0.05) and the control. However, the patients of the control group showed no statistically significant differences before and after treatment either in Qmax ([15.4 ± 3.4] vs [16.1 ± 2.9] ml/s, P>0.05) or in Qave ([10.9 ± 2.4] vs [11.1 ± 2.9] ml/s, P>0.05).

CONCLUSIONS

TCM fumigation combined with Levofloxacin is an effective therapy for type ⅢA prostatitis with the symptoms of damp heat and blood stasis, which can significantly improve the symptoms, reduce the NIHCPSI score, and increase the Qmax and Qave of the patient.

摘要

目的

探讨中药熏蒸治疗湿热瘀阻型ⅢA 前列腺炎的临床疗效。

方法

将72例湿热瘀阻型ⅢA 前列腺炎患者随机分为试验组和对照组,每组各36例。试验组采用中药熏蒸联合口服左氧氟沙星治疗,对照组单纯口服左氧氟沙星治疗。治疗4周后,比较两组患者的美国国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)评分、中医症状评分、最大尿流率(Qmax)和平均尿流率(Qave)。

结果

试验组总有效率显著高于对照组(91.7% 对61.1%,P<0.01);试验组治疗后NIH-CPSI评分较治疗前明显降低(14.5±8.2对26.5±9.3,P<0.05),且显著低于对照组(14.5±8.2对20.6±7.9,P<0.05)。试验组治疗后Qmax较治疗前显著增加([21.2±4.3]对[15.8±3.6]ml/s,P<0.05),且高于对照组;Qave较治疗前也显著增加([16.3±3.5]对[10.5±2.8]ml/s,P<0.05),且高于对照组。而对照组治疗前后Qmax([15.4±3.4]对[16.1±2.9]ml/s,P>0.05)及Qave([10.9±2.4]对[11.1±2.9]ml/s,P>0.05)差异均无统计学意义。

结论

中药熏蒸联合左氧氟沙星治疗湿热瘀阻型ⅢA 前列腺炎疗效显著,可明显改善患者症状,降低NIH-CPSI评分,提高Qmax和Qave。

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