Emori M, Shimizu J, Murahashi Y, Mizushima E, Sugita S, Hasegawa T, Yamashita T
Sapporo Medical University , Japan.
Ann R Coll Surg Engl. 2018 May;100(5):e128-e131. doi: 10.1308/rcsann.2018.0061. Epub 2018 Apr 16.
Nodular fasciitis (NF) is a self-limiting fibrous neoplasm that can be mistaken for a soft tissue sarcoma. It is characterised by rapid growth, slight pain and local tenderness. Although it is frequently found in the forearm, a lesion distal to the wrist is quite rare. We present two unusual cases of NF involving the palm, supported by detecting ubiquitin specific protease 6 gene rearrangement. The first patient had non-intraneural NF presenting as peripheral neuropathy affecting the digital nerve while the second patient suffered from painless, non-tender NF in the palm, which had not regressed spontaneously during the five months prior to surgery.
结节性筋膜炎（NF）是一种自限性纤维性肿瘤，可被误诊为软组织肉瘤。其特点是生长迅速、轻微疼痛和局部压痛。虽然它常在前臂发现，但手腕远端的病变相当罕见。我们报告两例不寻常的累及手掌的结节性筋膜炎病例，通过检测泛素特异性蛋白酶6基因重排得以证实。首例患者为非神经内结节性筋膜炎，表现为影响指神经的周围神经病变，而第二例患者手掌出现无痛、无压痛的结节性筋膜炎，在手术前五个月未自发消退。
