a Neurology, Public Health and Disability Unit , Neurological Instiute C. Besta, IRCCS Foundation , Milan , Italy.
b Department of Neuroimmunology and Neuromuscular Diseases , Neurological Institute C. Besta, IRCCS Foundation , Milan , Italy.
Disabil Rehabil. 2019 Sep;41(19):2255-2263. doi: 10.1080/09638288.2018.1461937. Epub 2018 Apr 16.
This cross-sectional study aims to identify the predictors of work-related difficulties in a sample of employed persons with multiple sclerosis as addressed with the Multiple Sclerosis Questionnaire for Job Difficulties. Hierarchical linear regression analysis was conducted to identify predictors of work difficulties: predictors included demographic variables (age, formal education), disease duration and severity, perceived disability and psychological variables (cognitive dysfunction, depression and anxiety). The targets were the questionnaire's overall score and its six subscales. A total of 177 participants (108 females, aged 21-63) were recruited. Age, perceived disability and depression were direct and significant predictors of the questionnaire total score, and the final model explained 43.7% of its variation. The models built on the questionnaire's subscales show that perceived disability and depression were direct and significant predictors of most of its subscales. Our results show that, among patients with multiple sclerosis, those who were older, with higher perceived disability and higher depression symptoms have more and more severe work-related difficulties. The Multiple Sclerosis Questionnaire for Job Difficulties can be fruitfully exploited to plan tailored actions to limit the likelihood of near-future job loss in persons of working age with multiple sclerosis. Implications for rehabilitation Difficulties with work are common among people with multiple sclerosis and are usually addressed in terms of unemployment or job loss. The Multiple Sclerosis Questionnaire for Job Difficulties is a disease-specific questionnaire developed to address the amount and severity of work-related difficulties. We found that work-related difficulties were associated to older age, higher perceived disability and depressive symptoms. Mental health issues and perceived disability should be consistently included in future research targeting work-related difficulties.
这项横断面研究旨在通过使用多发性硬化症工作困难问卷（Multiple Sclerosis Questionnaire for Job Difficulties）识别有工作的多发性硬化症患者群体中与工作相关的困难的预测因素。采用分层线性回归分析来识别工作困难的预测因素：预测因素包括人口统计学变量（年龄、正规教育）、疾病持续时间和严重程度、感知残疾和心理变量（认知功能障碍、抑郁和焦虑）。目标是问卷的总分及其六个子量表。共招募了 177 名参与者（108 名女性，年龄 21-63 岁）。年龄、感知残疾和抑郁是问卷总分的直接和显著预测因素，最终模型解释了其 43.7%的变化。基于问卷子量表建立的模型表明，感知残疾和抑郁是其大多数子量表的直接和显著预测因素。我们的研究结果表明，在多发性硬化症患者中，年龄较大、感知残疾较高和抑郁症状较重的患者与工作相关的困难更多且更严重。多发性硬化症工作困难问卷可有效地用于制定有针对性的行动方案，以限制处于工作年龄的多发性硬化症患者在不久的将来失业的可能性。康复的意义 工作困难在多发性硬化症患者中很常见，通常涉及失业或失去工作。多发性硬化症工作困难问卷是一种针对特定疾病的问卷，旨在解决与工作相关的困难程度和严重程度。我们发现，工作相关的困难与年龄较大、感知残疾程度较高和抑郁症状有关。心理健康问题和感知残疾应在未来针对工作相关困难的研究中持续纳入。
