private practice in Berwick, Australia.
GC Aesthetics, Glasgow, United Kingdom.
Aesthet Surg J. 2019 Jan 1;39(1):56-63. doi: 10.1093/asj/sjy091.
Anaplastic large cell lymphoma (ALCL) is a rare form of lymphoma involving cells of the immune system. It is currently gaining interest because of an association between the development of ALCL and an increased risk in women who have had breast implant surgery. Although not confirmed, many theories exist as to the etiology of this association in women, and there is growing concern that ALCL is more prevalent in women with textured breast implants. In particular, the risk of developing ALCL appears to be related to increasing implant texturization or "surface roughness." This paper examines the current manner of defining and characterizing breast implant surface texture and challenges the appropriateness of applying this technology and linking it to ALCL. It is not a comprehensive review of the etiology of capsular contracture and ALCL, but it proposes an alternative perspective on surface texture measurements from that currently employed and its role in researching the etiology of ALCL. The authors hope that their article will provoke thought and reflection when considering the issues currently being highlighted with regard to texturing of breast implants.
间变性大细胞淋巴瘤（ALCL）是一种罕见的淋巴瘤，涉及免疫系统的细胞。由于 ALCL 的发展与接受过乳房植入手术的女性的风险增加之间存在关联，目前人们对其产生了兴趣。尽管尚未得到证实，但针对这种女性关联存在许多理论，人们越来越担心具有纹理乳房植入物的女性中 ALCL 更为普遍。具体而言，发展为 ALCL 的风险似乎与植入物的纹理化或“表面粗糙度”增加有关。本文探讨了当前定义和描述乳房植入物表面纹理的方式，并质疑了应用该技术并将其与 ALCL 联系起来的适当性。本文不是对包膜挛缩和 ALCL 的病因的全面综述，而是从目前使用的角度提出了对表面纹理测量的替代观点及其在研究 ALCL 病因中的作用。作者希望当考虑当前突出强调的乳房植入物纹理问题时，他们的文章能够引起人们的思考和反思。
