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剪切波弹性成像技术评估桥本甲状腺炎的弹性。

ShearWave™ elastography for evaluation of the elasticity of Hashimoto's thyroiditis.

机构信息

Department of Ultrasound Diagnosis, Capital Medical University Affiliated Beijing Anzhen Hospital, Beijing, P.R. China.

Department of Endocrinology Diagnosis, Capital Medical University Affiliated Beijing Anzhen Hospital, Beijing, P.R. China.

出版信息

Clin Hemorheol Microcirc. 2022;80(1):9-16. doi: 10.3233/CH-170347.

Abstract

The aim of this study was to assess the elasticity of Hashimoto's thyroiditis in the different processes via supersonic ShearWave™ Elastography (SWE™). Quantitative information is delivered as Young's modulus value expressed in kilo-Pascal (kPa). 30 healthy female and 30 healthy male individuals aging at 40±20 y had undergone conventional ultrasonography and SWE to determine the influence of gender on elasticity of thyroid. Also 60 female and 60 male patients (mean age, 40±20 y) with Hashimoto's thyroiditis in different processes underwent conventional ultrasonography and SWE to determine the elasticity of thyroid in Hashimoto's thyroiditis. Furthermore, the relationship between elasticity values and thyroid peroxidase antibody (TPOAB) in the patients was investigated. We found significant impact of gender on elasticity values of healthy thyroids. Our study showed that increased elasticity values with statistical significance in hyperthyroidism stage, normal thyroid function stage and hypothyroidism were shown. Low degree relationship between elasticity values and TPOAB was found in 60 male patients. However, there was no such correlation in female patients.

摘要

本研究旨在通过超声剪切波弹性成像(SWE)评估桥本甲状腺炎不同病程中的弹性。定量信息以千帕斯卡(kPa)表示的杨氏模量值形式提供。30 名年龄在 40±20 岁的健康女性和 30 名健康男性接受了常规超声和 SWE,以确定性别对甲状腺弹性的影响。此外,60 名年龄在 40±20 岁的不同病程的桥本甲状腺炎女性和 60 名男性患者接受了常规超声和 SWE,以确定桥本甲状腺炎中甲状腺的弹性。此外,还研究了患者的弹性值与甲状腺过氧化物酶抗体(TPOAB)之间的关系。我们发现性别对健康甲状腺的弹性值有显著影响。我们的研究表明,在甲状腺功能亢进期、甲状腺功能正常期和甲状腺功能减退期,甲状腺的弹性值显著增加。在 60 名男性患者中,发现弹性值与 TPOAB 之间存在低度相关性。然而,在女性患者中则没有这种相关性。

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