甘油三酯作为红细胞血红蛋白氧结合特性的指标1。

Triglycerides as indicators of erythrocyte hemoglobin oxygen-binding properties1.

作者信息

Fornal Maria, Piergies Natalia, Pięta Ewa, Wrobel Tomasz P, Kwiatek Wojciech M, Paluszkiewicz Czesława, Królczyk Jarosław, Grodzicki Tomasz

机构信息

Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, Krakow, Poland.

Institute of Nuclear Physics Polish Academy of Sciences, Krakow, Poland.

出版信息

Clin Hemorheol Microcirc. 2018;69(1-2):289-294. doi: 10.3233/CH-189127.

DOI:10.3233/CH-189127

PMID:29660922

Abstract

OBJECTIVES

To assess the relationships of clinical and laboratory parameters, with erythrocyte oxygen concentration.

METHODS

The study group consisted of 47 healthy adults out of which 16 showed slightly higher blood pressure and were classified as individuals with prehypertension. For each individual, data were obtained on: systolic and diastolic blood pressure (SBP, DBP), blood morphology, lipids profile, fibrinogen, hs-CRP. The erythrocyte oxygen concentration was assessed with the Raman spectroscopy technique. Arithmetic means for all laboratory parameters were estimated by oxygen concentration tertiles and tested for statistical significance of linear trends across tertiles.

RESULTS

The multivariate regression analysis showed statistically significant negative relationship of triglycerides level with oxygen concentration.

CONCLUSIONS

A hypothesis has been formulated that triglycerides level is an indicator of the erythrocyte ability to transport oxygen to the tissues.

摘要

目的

评估临床和实验室参数与红细胞氧浓度之间的关系。

方法

研究组由47名健康成年人组成，其中16人的血压略高，被归类为高血压前期个体。针对每个个体，获取了以下数据：收缩压和舒张压（SBP、DBP）、血液形态、血脂谱、纤维蛋白原、高敏C反应蛋白。采用拉曼光谱技术评估红细胞氧浓度。通过氧浓度三分位数估计所有实验室参数的算术平均值，并检验三分位数间线性趋势的统计学显著性。