Khadadah Fatima, Callum Jeannie, Shelton Dominick, Lin Yulia
Faculty of Medicine, University of Toronto, Toronto, Canada.
Department of Laboratory Medicine & Molecular Diagnostics, Sunnybrook Health Sciences Centre, and Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Canada.
Transfusion. 2018 Aug;58(8):1902-1908. doi: 10.1111/trf.14626. Epub 2018 Apr 17.
Patients presenting to the emergency department (ED) with iron deficiency anemia (IDA) are underrecognized, undertreated with iron, and overtransfused. A 3-month audit of red blood cell (RBC) transfusions at the Sunnybrook Health Sciences Centre ED in 2013 showed that only 53% of transfusions for IDA were appropriate. The aim of this quality improvement project was to increase the rate of appropriate transfusion to greater than 80%.
Since November 2013, several quality improvement interventions have been implemented, including educational presentations, development of an algorithm on IDA management in the ED, and development of an ED IDA toolkit. The primary outcome was appropriateness of RBC transfusions per month. The process measure was monthly intravenous (IV) iron use in IDA patients managed exclusively by ED staff. Balancing measures included IV iron use according to the algorithm and undertransfusion.
Over a 24-month period beginning January 2014, assessment of 193 units transfused in the ED showed an improvement of RBC appropriateness to 91% (range 50%-100%). IV iron use increased from one dose in the 3-month audit to an average of 2.6 and 4.7 per month in 2014 and 2015, respectively. IV iron use did not follow the algorithm in 19% (18 of 93) of cases: 12 were given to patients with less severe iron deficiency or bleeding.
Improved RBC transfusion appropriateness for IDA in the ED can be achieved and maintained with the implementation of simple educational and practical interventions.
因缺铁性贫血(IDA)前往急诊科(ED)就诊的患者未得到充分识别,铁剂治疗不足且输血过度。2013年在桑尼布鲁克健康科学中心急诊科对红细胞(RBC)输血进行的为期3个月的审核显示,IDA输血中仅有53%是合适的。本质量改进项目的目标是将合适输血率提高至80%以上。
自2013年11月起,实施了多项质量改进干预措施,包括开展教育讲座、制定急诊科IDA管理算法以及开发急诊科IDA工具包。主要结局是每月RBC输血的合适性。过程指标是仅由急诊科工作人员管理的IDA患者每月静脉注射铁剂的使用情况。平衡指标包括按照算法使用静脉铁剂和输血不足。
从2014年1月开始的24个月期间,对急诊科输注的193个单位进行评估,结果显示RBC合适率提高到了91%(范围为50%-100%)。静脉铁剂的使用从3个月审核时的一剂增加到2014年平均每月2.6剂和2015年平均每月4.7剂。19%(93例中的18例)的病例未按照算法使用静脉铁剂:其中12例给予了缺铁或出血情况较轻的患者。
通过实施简单的教育和实际干预措施,可实现并维持急诊科IDA患者RBC输血合适率的提高。