Sharma Munish, Neupane Ritesh, Khalighi Koroush
Department of Internal Medicine, Easton Hospital, Easton, PA, USA.
Electrophysiology Lab, Easton Hospital, Easton, PA, USA.
Am J Case Rep. 2018 Apr 18;19:458-461. doi: 10.12659/ajcr.908654.
BACKGROUND Poorly controlled ventricular rate associated with atrial fibrillation (AF) leads to tachycardia-induced left ventricular dysfunction. Atrioventricular (AV) nodal ablation and cardiac pacing is the standard of care in refractory congestive heart failure (CHF) due to AF with moderate to rapid ventricular response that failed conventional medical therapy. If the patient is not a candidate for AF ablation with pulmonary vein isolation and elimination of AF foci, this is an effective approach, but it does have some challenges when done in a patient with dextrocardia and situs inversus. CASE REPORT Our patient was a 77-year-old woman with dextrocardia and situs inversus, with a history of permanent AF due to severe coronary artery disease (CAD), who suffered from recurrent CHF exacerbations from permanent AF with moderate to rapid ventricular response with underlying hypertensive cardiovascular disease. She was a poor candidate for pulmonary vein isolation because of her permanent AF status and high risk of recurrence. She underwent a technically challenging AV nodal ablation with cardiac pacing due to the complex anatomy, with drastic improvement of symptoms within the next 24 h. CONCLUSIONS AV nodal ablation with cardiac pacing is the standard of care in patients with refractory AF with moderate to rapid ventricular response who have failed medical therapy and are not candidates for pulmonary vein isolation.
与心房颤动(AF)相关的心室率控制不佳会导致心动过速诱发的左心室功能障碍。房室(AV)结消融和心脏起搏是因AF伴中度至快速心室反应且常规药物治疗无效而导致的难治性充血性心力衰竭(CHF)的标准治疗方法。如果患者不适合进行肺静脉隔离和消除AF病灶的AF消融,这是一种有效的方法,但在右位心和内脏反位的患者中进行时确实存在一些挑战。病例报告:我们的患者是一名77岁的女性,患有右位心和内脏反位,有因严重冠状动脉疾病(CAD)导致的永久性AF病史,因永久性AF伴中度至快速心室反应以及潜在的高血压性心血管疾病而反复发生CHF加重。由于她的永久性AF状态和复发风险高,她不适合进行肺静脉隔离。由于解剖结构复杂,她接受了具有技术挑战性的AV结消融和心脏起搏,术后24小时内症状得到显著改善。结论:对于药物治疗无效且不适合进行肺静脉隔离的中度至快速心室反应的难治性AF患者,AV结消融和心脏起搏是标准治疗方法。