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65岁以上患者晕厥和短暂意识丧失的1年预后:188例多中心研究

[1-year prognosis of syncope and brief loss of consciousness in patients over 65. A multicenter study of 188 cases].

作者信息

Houdent C, Morcamp D, Séréni D, Conri C, Colvez A, Delgove H, Vinceneux P, Pibarot M L, Grosshans C, Peter B

机构信息

Service de Médecine interne, Hôpital de Boisguillaume.

出版信息

Presse Med. 1988 Apr 9;17(13):626-9.

PMID:2966936
Abstract

The one-year outcome of syncope and transient loss of consciousness was studied prospectively in 188 patients aged over 65 admitted to internal medicine departments. Thirty-seven patients (19.6 p. 100) died. This mortality rate at one year was 2.34 times higher than that of a non-hospitalized french population of the same age group (standardized mortality ratio, SMR = 2.34, P less than 0.001). The frequency of sudden death (7 cases) was much higher than that observed in the reference population (0.05 expected deaths, P less than 0.0001). Overmortality was clearly apparent in groups with an initial diagnosis of heart disease (SMR = 2.36, P less than 0.01) or neurological disease (SMR = 4.25, P less than 0.001). The relapse rate was 28 p. 100 globally and up to 43 p. 100 in cardiac patients. In the group with iatrogenic symptoms treatment was appropriately corrected in 86 p. 100 of the patients, and none of these relapsed. One year after the initial episode 11 p. 100 of the surviving patients had been institutionalized.

摘要

对188名65岁以上入住内科的患者晕厥和短暂性意识丧失的一年期转归进行了前瞻性研究。37名患者(19.6%)死亡。这一一年期死亡率比同年龄组未住院的法国人群高2.34倍(标准化死亡率,SMR = 2.34,P < 0.001)。猝死发生率(7例)远高于参照人群(预期死亡0.05例,P < 0.0001)。初始诊断为心脏病(SMR = 2.36,P < 0.01)或神经疾病(SMR = 4.25,P < 0.001)的组中,超额死亡率明显。总体复发率为28%,心脏病患者复发率高达43%。在有医源性症状的组中,86%的患者治疗得到适当纠正,且这些患者均未复发。初次发作一年后,11%的存活患者被送进了养老院。

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