Qiao Pan, Xu Tian-Tong, Zhang Wen, Tian Rong
Department of Spine Surgery, Tianjin Union Medical Center, 190 jieyuan Road, Hongqiao District, Tianjin, 300121, People's Republic of China.
Department of Pediatrics, Tianjin Children's Hospital, Tianjin, 300000, China.
J Orthop Surg Res. 2018 Apr 18;13(1):90. doi: 10.1186/s13018-018-0805-2.
The distribution and related factors of Modic changes (MC) in the lumbar spine has been evaluated. In the present study, the MC in the cervical endplate of patients with cervical spondylotic myelopathy (CSM) was investigated.
A total of 6422 cervical endplates of 539 patients suffered from CSM (259 males and 280 females) with mean age of 46 ± 5.2 years. All patients underwent MRI scans and X-ray for evaluating the distribution of MC. The clinical information were recorded.
It was observed that 13.0% of patients and 2.4% of endplates showed MC. There were 3.7, 7.6, and 1.7% of cases diagnosed as types I, II, and III, respectively, suggesting MC were corrected with disc degeneration. The incidence rates of MC were 0, 0.3, 0.6, 0.9, 0.7, and 0.2%, respectively, in different intervertebral disc segments C, C, C, C, C, and CT. Disc degeneration, segment, disease course, and age were statistically related to the MC. Patients over the age of 40 more easily suffered from MC.
MCs manifested as type II mainly in patients with CSM. The incidence was highest in the C segment. Disc degeneration greatly contributed to the occurrence of MC.
已对腰椎Modic改变（MC）的分布及相关因素进行了评估。在本研究中，对脊髓型颈椎病（CSM）患者颈椎终板的MC进行了调查。
共纳入539例CSM患者（男259例，女280例）的6422个颈椎终板，平均年龄46±5.2岁。所有患者均接受MRI扫描和X线检查以评估MC的分布，并记录临床信息。
观察到13.0%的患者和2.4%的终板出现MC。分别有3.7%、7.6%和1.7%的病例被诊断为I型、II型和III型，提示MC与椎间盘退变相关。在不同椎间盘节段C、C、C、C、C和CT中，MC的发生率分别为0、0.3%、0.6%、0.9%、0.7%和0.2%。椎间盘退变、节段、病程和年龄与MC在统计学上相关。40岁以上患者更容易发生MC。
CSM患者的MC主要表现为II型。C节段的发生率最高。椎间盘退变对MC的发生起很大作用。
