Newbrun E
Aust Dent J. 1979 Aug;24(4):231-4. doi: 10.1111/j.1834-7819.1979.tb02930.x.
Dental plaque consists of a dynamic microbiota which responds to ecological changes. There are major technical difficulties in obtaining representative plaque samples and in dispersing, cultivating, identifying and quantifying the microbial components. Cumulative findings on plaque microbiota associated with dental caries and different forms of periodontal disease support the specific plaque hypothesis. However, the data do not permit designation of any single organism as the distinct aetiological agent. The characteristic pattern is autogenic succesion, in which one or more microbial species alter the plaque environment and are replaced or succeeded by other species.
牙菌斑由动态的微生物群组成,该微生物群会对生态变化做出反应。获取具有代表性的菌斑样本以及对微生物成分进行分散、培养、鉴定和定量分析存在重大技术困难。关于与龋齿和不同形式牙周疾病相关的菌斑微生物群的累积研究结果支持了特异性菌斑假说。然而,这些数据并不允许将任何单一微生物指定为独特的病原体。其特征模式是自生演替,即一种或多种微生物物种改变菌斑环境,并被其他物种取代或接替。