[良性颅内高压与米诺环素]
[Benign intracranial hypertension and minocycline].
作者信息
Lubetzki C, Sanson M, Cohen D, Schaison-Cusin M, Lhermitte F, Lyon-Caen O
机构信息
Clinique de Neurologie et de Neuropsychologie, Hôpital de la Salpêtrière, Paris, France.
出版信息
Rev Neurol (Paris). 1988;144(3):218-20.
A 19 year-old woman complained of headache and nausea occurring while she was taking minocycline for acne. Examination showed bilateral papilloedema and a bilateral VIth nerve palsy. Symptoms and signs rapidly resolved after the drug was stopped. Benign intracranial hypertension due to tetracyclines is well known in infants. It is rare in adults. Its pathophysiology remains unknown. The role of vitamin A is inconsistent. Others biological factors or personal susceptibility could be involved.
一名19岁女性在服用米诺环素治疗痤疮时出现头痛和恶心症状。检查发现双侧视乳头水肿和双侧第六神经麻痹。停药后症状和体征迅速缓解。四环素导致的良性颅内高压在婴儿中很常见。在成人中则很少见。其病理生理学尚不清楚。维生素A的作用并不一致。可能涉及其他生物学因素或个人易感性。
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