Halevy A, Offer I, Garty B
Pediatric Dept. A, Schneider Children's Hospital, Petah Tikva.
Harefuah. 1998 May 15;134(10):765-6, 831.
A 15-year-old girl, who had been treated with minocyclin for acne for 2 months, was admitted for investigation of headache, nausea and papilledema. A space-occupying lesion was ruled out by computerized brain tomography. The diagnosis of benign intracranial pressure (pseudo-tumor cerebri) was made because of elevated cerebrospinal fluid pressure with normal biochemistry and cytology. Tetracyclines, especially minocyclin, commonly used for treating acne in adolescents, can cause benign intracranial pressure.
一名15岁女孩因痤疮服用米诺环素2个月后,因头痛、恶心和视乳头水肿入院检查。脑部计算机断层扫描排除了占位性病变。由于脑脊液压力升高但生化和细胞学检查正常,诊断为良性颅内压增高(假性脑瘤)。四环素,尤其是米诺环素,常用于治疗青少年痤疮,可导致良性颅内压增高。