Research Center for Food and Development, CIAD, A.C., Carretera a La Victoria Km. 0.6, Hermosillo, Sonora 83304, Mexico.
Molecules. 2018 Apr 18;23(4):942. doi: 10.3390/molecules23040942.
Pectins are plant cell wall natural heteropolysaccharides composed mainly of α-1-4 d-galacturonic acid units, which may or may not be methyl esterified, possesses neutral sugars branching that harbor functional moieties. Physicochemical features as pH, temperature, ions concentration, and cosolute presence, affect directly the extraction yield and gelling capacity of pectins. The chemical and structural features of this polysaccharide enables its interaction with a wide range of molecules, a property that scientists profit from to form new composite matrices for target/controlled delivery of therapeutic molecules, genes or cells. Considered a prebiotic dietary fiber, pectins meetmany regulations easily, regarding health applications within the pharmaceutical industry as a raw material and as an agent for the prevention of cancer. Thus, this review lists many emergent pectin-based composite materials which will probably palliate the impact of obesity, diabetes and heart disease, aid to forestall actual epidemics, expand the ken of food additives and food products design.
果胶是一种植物细胞壁天然杂多糖,主要由α-1-4 d-半乳糖醛酸单元组成,可能甲酯化,也可能不甲酯化,具有中性糖分支,携带功能部分。理化性质如 pH 值、温度、离子浓度和共溶质的存在,直接影响果胶的提取产率和胶凝能力。这种多糖的化学和结构特征使其能够与广泛的分子相互作用,科学家们利用这一特性来形成新的复合基质,用于目标/控制释放治疗分子、基因或细胞。果胶被认为是一种益生元膳食纤维,很容易满足许多法规,在制药行业作为一种原料,作为预防癌症的一种药物。因此,本综述列出了许多新兴的果胶基复合材料,这些复合材料可能会减轻肥胖、糖尿病和心脏病的影响,有助于预防实际的流行病,扩大食品添加剂和食品产品设计的范围。