Husslein P, Egarter C
I. Universitäts-Frauenklinik, Wien.
Wien Klin Wochenschr. 1988 Mar 4;100(5):157-9.
The recent trend towards conservative management of tubal pregnancies, as well as first reports on the efficacy of systemic or local administration of prostaglandins prompted us to investigate the therapeutic effect of PGF2 alpha injected directly into a non-ruptured tubal pregnancy, followed by systemic administration of a synthetic longer-acting PGE 2 derivative for 3 days. Serial determinations of hormone parameters in the follow up of this patient verified that this combination treatment is capable of dealing with tubal pregnancy without further surgical treatment. Hysterosalpingography performed 6 weeks afterwards showed tubal patency on both sides.
近期对输卵管妊娠采取保守治疗的趋势，以及关于前列腺素全身或局部给药疗效的初步报告，促使我们研究将PGF2α直接注射到未破裂的输卵管妊娠中，随后连续3天全身给予合成的长效PGE2衍生物的治疗效果。对该患者随访过程中的激素参数进行系列测定证实，这种联合治疗能够在无需进一步手术治疗的情况下处理输卵管妊娠。6周后进行的子宫输卵管造影显示双侧输卵管通畅。
