Takahashi K, Watanabe M, Kikuchi J, Kishi H, Saito K, Mouri H, Ikeno N, Endo H, Shima I, Morizuka T
Dept. of Obstetrics and Gynecology, Sendai National Hospital, Japan.
Gan To Kagaku Ryoho. 1988 May;15(5):1777-81.
Neocarzinostatin (NCS) was administered intravenously by drop infusion to 16 patients with ovarian cancer, and intrathoracically to one patient. In addition to evaluation of the efficacy of the chemotherapy, we mainly investigated its effect on ascites and pleural effusion, and carried out continuous measurements of the abdominal circumference in 3 patients. NCS relieved thoracic effusion in 1 patient. We observed that abdominal circumference decreased in 10 patients after administration of NCS. The results obtained from continuous measurement of abdominal circumference revealed that NCS significantly reduced ascitic retention in ovarian cancer.
对16例卵巢癌患者静脉滴注新制癌菌素（NCS），对1例患者进行胸腔内给药。除评估化疗疗效外，我们主要研究了其对腹水和胸腔积液的影响，并对3例患者进行了腹围的连续测量。NCS使1例患者的胸腔积液得到缓解。我们观察到，给予NCS后，10例患者的腹围减小。腹围连续测量结果显示，NCS可显著减少卵巢癌患者的腹水潴留。
