Shelton Trevor J, Skaggs Alton W, Pereira Gavin C
Department of Orthopaedics, University of California, Davis, 4860 Y Street, Suite 3800, Sacramento, CA 95817, USA.
School of Medicine, University of California, Davis, Sacramento, CA 95817, USA.
Case Rep Orthop. 2018 Feb 19;2018:8657562. doi: 10.1155/2018/8657562. eCollection 2018.
We report a novel case of a patient who had a draining sinus soon after a total hip arthroplasty that spontaneously resolved. The patient voluntarily discontinued antibiotic suppressive therapy (AST) after 10 years of treatment and paradoxically experienced full resolution of signs of chronic prosthetic joint infection (PJI), including recovery of his left-sided draining sinus tract. Now 8 years after discontinuing AST, the patient has no pain, good function, and no major or minor criteria of joint infection according to the Musculoskeletal Infection Society (MSIS) workgroup. The authors have not identified literature describing a similar resolution of draining sinus tracts from around a prosthetic joint after discontinuing AST. Despite the resolution of this patient's sinus tract, the authors do not advocate for discontinuing AST in patients with a draining sinus tract. However, in spite of the fact that the MSIS consensus statement suggests that a draining sinus is a sure sign of PJI and that the assumption is that the infection will not go away until explant, this case was different.
我们报告了一例全髋关节置换术后不久出现引流窦道但自行愈合的新病例。该患者在接受了10年的抗生素抑制治疗(AST)后自行停药,然而令人意想不到的是,慢性人工关节感染(PJI)的症状完全消失了,包括左侧引流窦道也愈合了。在停用AST 8年后,患者没有疼痛,功能良好,根据肌肉骨骼感染学会(MSIS)工作组的标准,没有关节感染的主要或次要标准。作者尚未发现文献描述在停用AST后人工关节周围引流窦道有类似的愈合情况。尽管该患者的窦道已经愈合,但作者并不主张对有引流窦道的患者停用AST。然而,尽管MSIS的共识声明表明引流窦道是PJI的明确迹象,并且一般认为在植入物取出之前感染不会消除,但这个病例却有所不同。